• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童颅内非脑膜附着性异时性脑膜瘤——罕见病例报告及文献复习。

Metachronous intracranial meningiomas without dural attachment in a child - Rare case report and review of literature.

机构信息

Department of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, 560029, Karnataka, India.

Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, 560029, Karnataka, India.

出版信息

Childs Nerv Syst. 2024 Dec;40(12):4265-4269. doi: 10.1007/s00381-024-06582-7. Epub 2024 Aug 24.

DOI:10.1007/s00381-024-06582-7
PMID:39180697
Abstract

INTRODUCTION

Meningiomas in children are rare, constituting less than 5% of all paediatric brain tumours and less than 2% of all meningiomas. Multiple meningiomas (synchronous or metachronous) are even more uncommon, typically occurring due to radiation exposure or in patients with phacomatoses like Neurofibromatosis II. This report presents the case of a child with metachronous meningiomas without dural attachment in unusual locations, along with their management.

PURPOSE

This report aims to describe a rare paediatric case of metachronous meningiomas without dural attachment, detailing their presentation, treatment, and outcomes.

CASE DETAILS

A 2-year-old female presented with headaches, irritability, and excessive crying for one year. A CT scan revealed a mass in the fourth ventricle, causing obstruction, which was surgically decompressed. The biopsy confirmed a clear cell meningioma, WHO grade II. A follow-up MRI identified a new lesion in the suprasellar area six months later, for which she underwent right pterional craniotomy and gross total resection, which turned out to be a clear cell meningioma, WHO grade II. The patient recovered well and remained asymptomatic, with no recurrence on MRI at one-year follow-up.

CONCLUSION

This case highlights the unusual presentation of metachronous clear cell meningiomas without dural attachment in a young child. Surgical excision resulted in a favourable outcome, though long-term follow-up is essential due to the high propensity for recurrence.

摘要

介绍

儿童脑膜瘤较为罕见,占儿童脑肿瘤的比例不到 5%,占所有脑膜瘤的比例不到 2%。多发性脑膜瘤(同时性或异时性)更为罕见,通常由于辐射暴露或神经纤维瘤病 II 等神经皮肤疾病而发生。本报告介绍了一例无硬脑膜附着的异时性脑膜瘤患儿的病例,以及其治疗情况。

目的

本报告旨在描述一例罕见的儿童异时性无硬脑膜附着脑膜瘤病例,详细描述其表现、治疗和结果。

病例详情

一名 2 岁女性因头痛、烦躁和过度哭泣一年就诊。CT 扫描显示第四脑室有一肿块,导致梗阻,行手术减压。活检证实为 II 级透明细胞脑膜瘤。6 个月后,随访 MRI 发现鞍上区出现新病变,行右侧翼点开颅肿瘤全切除,结果为 II 级透明细胞脑膜瘤。患者恢复良好,无症状,1 年随访时 MRI 未见复发。

结论

本例突出了儿童罕见的异时性无硬脑膜附着透明细胞脑膜瘤的表现。手术切除结果良好,但由于复发倾向高,需要长期随访。

相似文献

1
Metachronous intracranial meningiomas without dural attachment in a child - Rare case report and review of literature.儿童颅内非脑膜附着性异时性脑膜瘤——罕见病例报告及文献复习。
Childs Nerv Syst. 2024 Dec;40(12):4265-4269. doi: 10.1007/s00381-024-06582-7. Epub 2024 Aug 24.
2
Cisterna magna meningiomas without dural attachment: Report of two cases.无硬脑膜附着的枕大池脑膜瘤:2例报告
Neurol Neurochir Pol. 2017 May-Jun;51(3):247-251. doi: 10.1016/j.pjnns.2017.02.003. Epub 2017 Mar 2.
3
Posterior fossa clear cell meningioma without dural attachment in a child.一名儿童的后颅窝透明细胞型脑膜瘤,无硬脑膜附着。
Childs Nerv Syst. 2009 Mar;25(3):389-92. doi: 10.1007/s00381-008-0757-7. Epub 2008 Nov 22.
4
Association of meningiomas with dural "tails"; surgical significance.脑膜瘤与硬脑膜“尾征”的关联;手术意义。
Acta Neurochir (Wien). 1992;114(1-2):59-63. doi: 10.1007/BF01401115.
5
Meningioma of the pituitary stalk without dural attachment: case report and review of the literature.无硬脑膜附着的垂体柄脑膜瘤:病例报告及文献复习
Neurosurgery. 1999 Dec;45(6):1474-7. doi: 10.1097/00006123-199912000-00042.
6
Deep sylvian fissure meningioma without dural attachment in an adult: case report.成人无硬脑膜附着的大脑外侧裂深部脑膜瘤:病例报告
Neurosurgery. 1994 Nov;35(5):944-6; discussion 946. doi: 10.1227/00006123-199411000-00021.
7
Malignant meningioma of the falx cerebri in a child: case report and literature review.镰状窦脑内恶性脑膜瘤:病例报告及文献复习。
Childs Nerv Syst. 2024 Dec;40(12):4295-4300. doi: 10.1007/s00381-024-06600-8. Epub 2024 Sep 6.
8
Clear cell meningioma of the fourth ventricle in a child: a case report and literature review.儿童第四脑室透明细胞型脑膜瘤:一例报告及文献复习
Pediatr Neurosurg. 2010;46(6):462-5. doi: 10.1159/000325072. Epub 2011 May 3.
9
A radiopathological classification of dural tail sign of meningiomas.脑膜瘤硬脑膜尾征的放射病理学分类。
J Neurosurg. 2012 Oct;117(4):645-53. doi: 10.3171/2012.6.JNS111987. Epub 2012 Jul 27.
10
Spinal extradural en plaque meningiomas: clinical features and long-term outcomes of 12 cases.脊柱硬膜外片状脑膜瘤:12例临床特征及长期预后
J Neurosurg Spine. 2014 Dec;21(6):892-8. doi: 10.3171/2014.7.SPINE13819. Epub 2014 Sep 19.

本文引用的文献

1
The 2021 WHO classification of central nervous system tumors: what neurologists need to know.2021 年世卫组织中枢神经系统肿瘤分类:神经科医生需要了解的内容。
Curr Opin Neurol. 2022 Dec 1;35(6):764-771. doi: 10.1097/WCO.0000000000001109. Epub 2022 Oct 3.
2
Pediatric meningiomas: 10-year experience with 39 patients.小儿脑膜瘤:39 例患者 10 年经验。
J Neurooncol. 2020 Sep;149(3):543-553. doi: 10.1007/s11060-020-03649-8. Epub 2020 Oct 16.
3
Management of pediatric CNS meningiomas: CCHE-57357 experience in 39 cases.小儿中枢神经系统脑膜瘤的管理:开罗儿童癌症医院(CCHE)57357中心39例病例经验
Childs Nerv Syst. 2019 Aug;35(8):1323-1331. doi: 10.1007/s00381-019-04156-6. Epub 2019 May 24.
4
Pediatric meningiomas: a report of 5 cases and review of literature.小儿脑膜瘤:5例报告并文献复习
Childs Nerv Syst. 2019 Nov;35(11):2219-2225. doi: 10.1007/s00381-019-04142-y. Epub 2019 Apr 18.
5
Spinal Clear Cell Meningioma: Clinical Study with Long-Term Follow-Up in 12 Patients.脊髓透明细胞型脑膜瘤:12例患者的长期随访临床研究
World Neurosurg. 2019 Feb;122:e415-e426. doi: 10.1016/j.wneu.2018.10.064. Epub 2018 Oct 18.
6
Pediatric Meningeal Tumors of the Sylvian Fissure Region without Dural Attachment: A Series of Three Patients and Review of the Literature.无硬脑膜附着的大脑外侧裂区小儿脑膜肿瘤:3例病例系列及文献复习
Surg J (N Y). 2016 May 26;2(2):e31-e36. doi: 10.1055/s-0036-1584166. eCollection 2016 Apr.
7
Pediatric meningiomas: 65-year experience at a single institution.小儿脑膜瘤:一家机构65年的经验
J Neurosurg Pediatr. 2017 Jul;20(1):42-50. doi: 10.3171/2017.2.PEDS16497. Epub 2017 May 5.
8
Suprasellar Clear Cell Meningioma in an Infant.婴儿鞍上透明细胞型脑膜瘤
Sultan Qaboos Univ Med J. 2016 Aug;16(3):e364-7. doi: 10.18295/squmj.2016.16.03.018. Epub 2016 Aug 19.
9
Anterior interhemispheric fissure meningioma without dural attachment in an adult.一名成年患者的前半球间裂脑膜瘤,无硬脑膜附着。
Neurol India. 2011 Jul-Aug;59(4):635-7. doi: 10.4103/0028-3886.84359.
10
Pediatric intracranial meningiomas--do they differ from their counterparts in adults?儿童颅内脑膜瘤——它们与成人的颅内脑膜瘤有差异吗?
Pediatr Neurosurg. 2008;44(1):43-8. doi: 10.1159/000110661. Epub 2007 Dec 14.