Department of Rehabilitation Medicine, CNPC Central Hospital, Langfang, 065000, PR China.
Department of Rehabilitation Medicine, The Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang, Hebei, 050051, PR China.
Stem Cell Res Ther. 2024 Aug 26;15(1):271. doi: 10.1186/s13287-024-03888-w.
In the last ten years, stem cell (SC) therapy has been extensively used to treat a range of conditions such as degenerative illnesses, ischemia-related organ dysfunction, diabetes, and neurological disorders. However, the clinical application of these therapies is limited due to the poor survival and differentiation potential of stem cells (SCs). Extracorporeal shock wave therapy (ESWT), as a non-invasive therapy, has shown great application potential in enhancing the proliferation, differentiation, migration, and recruitment of stem cells, offering new possibilities for utilizing ESWT in conjunction with stem cells for the treatment of different systemic conditions. The review provides a detailed overview of the advances in using ESWT with SCs to treat musculoskeletal, cardiovascular, genitourinary, and nervous system conditions, suggesting that ESWT is a promising strategy for enhancing the efficacy of SC therapy for various diseases.
在过去的十年中，干细胞 (SC) 疗法已被广泛用于治疗多种疾病，如退行性疾病、与缺血相关的器官功能障碍、糖尿病和神经紊乱。然而，由于干细胞 (SCs) 的生存能力和分化潜能较差，这些疗法的临床应用受到限制。体外冲击波疗法 (ESWT) 作为一种非侵入性疗法，在增强干细胞的增殖、分化、迁移和募集方面显示出巨大的应用潜力，为将 ESWT 与干细胞结合用于治疗不同的全身疾病提供了新的可能性。本综述详细介绍了将 ESWT 与干细胞联合用于治疗肌肉骨骼、心血管、泌尿生殖和神经系统疾病的进展，表明 ESWT 是增强干细胞疗法治疗各种疾病疗效的一种很有前途的策略。
