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弥漫性大B细胞淋巴瘤一例的不寻常表现。

Unusual presentation in a case of diffuse large B-cell lymphoma.

作者信息

Das Priya, Gupta Kaustubh, Raj Gaurav, Tandon Vini, Awasthi Namrata Punit, Parashar Yatendra

机构信息

Department of Radio-diagnosis, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Digdarshika, Vini's Pathology Laboratory, Department of Pathology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.

出版信息

Radiol Case Rep. 2024 Jul 31;19(10):4440-4444. doi: 10.1016/j.radcr.2024.06.074. eCollection 2024 Oct.

DOI:10.1016/j.radcr.2024.06.074
PMID:39185437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11342798/
Abstract

Non-Hodgkin's lymphoma are neoplasms derived from T cells and B cells and their precursors in the lymphoid system with higher susceptibility in involvement of extra-nodal sites. Predominant ureteric involvement is an unusual presentation. We present a case of diffuse large B-cell lymphoma with secondary involvement of ureter who had symptoms of urinary tract infection in absence of positive urine culture, non-responsive to broad spectrum antibiotics and masquerading pyogenic infection leading to pyelonephritis with ureteritis. Radiological examination revealed mass like soft tissue thickening of ureter extending from renal pelvis throughout the length of ureter. FNAC as well as biopsy from the periureteric thickening revealed lymphomatous involvement of ureter. The following case report provides insight on differentials and varied symptoms of lymphomatous involvement of ureter.

摘要

非霍奇金淋巴瘤是起源于淋巴系统中T细胞、B细胞及其前体细胞的肿瘤,结外部位受累的易感性较高。输尿管为主的受累是一种不寻常的表现。我们报告一例弥漫性大B细胞淋巴瘤继发输尿管受累的病例,该患者有尿路感染症状,但尿培养阴性,对广谱抗生素无反应,伪装成化脓性感染,导致肾盂肾炎伴输尿管炎。影像学检查显示输尿管有肿块样软组织增厚,从肾盂延伸至输尿管全长。细针穿刺抽吸活检以及输尿管周围增厚组织活检均显示输尿管有淋巴瘤累及。以下病例报告提供了输尿管淋巴瘤累及的鉴别诊断及多样症状的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/4af95e613b7f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/4a9c297f3322/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/386be77beb78/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/21153fd6dd09/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/4af95e613b7f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/4a9c297f3322/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/386be77beb78/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/21153fd6dd09/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b186/11342798/4af95e613b7f/gr4.jpg

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本文引用的文献

1
Multimodality imaging of renal lymphoma and its mimics.肾淋巴瘤及其类似病变的多模态成像
Insights Imaging. 2022 Aug 13;13(1):131. doi: 10.1186/s13244-022-01260-1.
2
Primary Diffuse Large B-Cell Lymphoma of the Urinary Bladder: Update on a Rare Disease and Potential Diagnostic Pitfalls.原发性膀胱弥漫性大 B 细胞淋巴瘤:罕见疾病的最新研究及潜在诊断陷阱。
Curr Oncol. 2022 Feb 10;29(2):956-968. doi: 10.3390/curroncol29020081.
3
Primary Diffuse Large B-Cell Lymphoma of the Urinary Tract: A Population-Based Analysis.原发性泌尿道弥漫性大B细胞淋巴瘤:一项基于人群的分析。
Front Oncol. 2021 Jul 14;11:609882. doi: 10.3389/fonc.2021.609882. eCollection 2021.
4
Twenty-year Experience with Genitourinary Lymphoma at a Community Hospital.社区医院 20 年泌尿生殖系统淋巴瘤诊治经验。
Clin Med Res. 2021 Jun;19(2):72-81. doi: 10.3121/cmr.2021.1531. Epub 2021 Mar 31.
5
Primary ureteral lymphoma presenting as bilateral obstructive uropathy.表现为双侧梗阻性尿路病的原发性输尿管淋巴瘤。
Urol Case Rep. 2020 Jun 9;33:101296. doi: 10.1016/j.eucr.2020.101296. eCollection 2020 Nov.
6
An unusual presentation of diffuse large B-cell lymphoma with ureteric involvement: A case report.弥漫性大B细胞淋巴瘤累及输尿管的罕见表现:一例报告
IJU Case Rep. 2018 Oct 21;2(1):5-8. doi: 10.1002/iju5.12024. eCollection 2019 Jan.
7
Clinical characteristics and outcomes of patients with diffuse large B cell lymphoma treated with R-CHOP-like or CHOP-like regimens: an 8-year experience from a single center.弥漫大 B 细胞淋巴瘤患者接受 R-CHOP 样或 CHOP 样方案治疗的临床特征和结局:单中心 8 年经验。
Ann Palliat Med. 2020 Jul;9(4):1442-1452. doi: 10.21037/apm-19-589. Epub 2020 Jul 2.
8
Primary non-Hodgkin lymphoma of kidney and ureter mimicking an upper tract urothelial carcinoma: A case report.酷似上尿路尿路上皮癌的肾脏及输尿管原发性非霍奇金淋巴瘤:一例报告
Urol Case Rep. 2019 Dec 13;29:101095. doi: 10.1016/j.eucr.2019.101095. eCollection 2020 Mar.
9
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South Asian J Cancer. 2019 Jan-Mar;8(1):57-59. doi: 10.4103/sajc.sajc_52_18.
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Int J Urol. 2019 Feb;26(2):148-159. doi: 10.1111/iju.13826. Epub 2018 Oct 29.