Auger Nathalie, Healy-Profitós Jessica, Côté-Corriveau Gabriel
University of Montreal Hospital Research Centre, Montreal, Quebec, Canada.
Institut national de santé publique du Québec, Montreal, Quebec, Canada.
Drug Alcohol Depend Rep. 2024 Jul 28;12:100264. doi: 10.1016/j.dadr.2024.100264. eCollection 2024 Sep.
To assess trends in hospitalization for sedative misuse among youth.
Using a serial cross-sectional design, we computed hospitalization rates for sedative-related suicide attempts, sedative use disorders, and other sedative poisonings within individuals aged 5-24 years in Quebec, Canada. We computed sedative-related hospitalization rates in 2006-2011, 2012-2017, and 2018-2023, and examined differences according to age, sex, polysubstance use, mental health comorbidity, and social vulnerability using rate ratios (RR) and 95 % confidence intervals (CI) comparing the last time period relative to the first.
Sedative-related hospitalization rates more than doubled during the study. Suicide attempts using sedatives increased from 50.5 per 100,000 youth in 2006-2011, to 82.2 in 2012-2017 and 114.4 in 2018-2023 (RR 2.26, 95 % CI 1.63-3.15), while sedative use disorders increased from 13.1 to 21.8 and 60.5 per 100,000 in these same time periods (RR 4.62, 95 % CI 2.54-8.40). Rates increased for 10-24 year-olds and in both sexes, particularly among youth with polysubstance use, anxiety and attention disorders, and social vulnerability.
Sedative misuse requiring hospitalization appears to be a growing issue among youth.
评估青少年镇静剂滥用的住院趋势。
采用系列横断面设计,我们计算了加拿大魁北克省5至24岁个体中与镇静剂相关的自杀未遂、镇静剂使用障碍和其他镇静剂中毒的住院率。我们计算了2006 - 2011年、2012 - 2017年和2018 - 2023年与镇静剂相关的住院率,并使用率比(RR)和95%置信区间(CI),通过比较最后一个时间段与第一个时间段,研究了年龄、性别、多物质使用、心理健康合并症和社会脆弱性方面的差异。
在研究期间,与镇静剂相关的住院率增加了一倍多。使用镇静剂的自杀未遂率从2006 - 2011年的每10万名青少年50.5例,增加到2012 - 2017年的82.2例和2018 - 2023年的114.4例(RR 2.26,95% CI 1.63 - 3.15),而在相同时间段内,镇静剂使用障碍率从每10万名青少年13.1例增加到21.8例和60.5例(RR 4.62,95% CI 2.54 - 8.40)。10至24岁的青少年以及男女两性的住院率均有所上升,特别是在有多物质使用、焦虑和注意力障碍以及社会脆弱性的青少年中。
需要住院治疗的镇静剂滥用在青少年中似乎是一个日益严重的问题。