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80 微米与 100 微米瓣飞秒 LASIK 治疗近视及近视散光的比较

Comparison between 80-microns versus 100-microns flap femtosecond LASIK for correction of myopia and myopic astigmatism.

机构信息

Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Ophthalmol. 2024 Sep 1;72(9):1308-1314. doi: 10.4103/IJO.IJO_3213_23. Epub 2024 Aug 23.

Abstract

PURPOSE

This study aimed to compare the safety, efficacy, and visual outcomes of 80-microns LASIK versus 100-microns LASIK in managing myopia and myopic astigmatism. The study was conducted at a tertiary care hospital in North India.

METHODS

This was a prospective contralateral eye study that included patients with myopia and myopic astigmatism seeking refractive correction. The eligibility criteria included normal corneal topography, an epithelial thickness less than 60 microns, a calculated percentage tissue ablation (with 100-microns flap) less than 40%, a calculated residual stromal bed thickness (with 100-microns flap) more than 300 microns, and willingness to participate and follow up. Patients with glaucoma, cataracts, other visually disabling ocular pathologies, and a history of past ocular surgery were excluded. All patients underwent LASIK with 80-microns LASIK in one eye and 100-microns LASIK in the other eye. The patients were followed up for 6 months, and the results were analyzed.

RESULTS

The study included 216 eyes of 108 patients. The mean preoperative spherical equivalent in the 80-microns group and the 100-microns group was -3.53 ± 1.81 and -3.69 ± 1.32 diopters, respectively (P = 0.78). The mean 6 months decimal postoperative UCVA was 0.98 ± 0.13 in the 80-microns group and 0.97 ± 0.14 in the 100-microns group (P = 0.99). The postoperative change in the higher-order aberration profile was comparable in both groups (P = 0.78). The percentage tissue ablation was significantly lower in the 80-microns group (P = 0.002). The incidence of flap micro striae and OBL was higher in the 80-microns group, while neither of these had any visual implications.

CONCLUSION

The study concluded that 80-microns LASIK is an efficacious and safe alternative to 100-micron LASIK, especially useful in patients with higher myopia.

摘要

目的

本研究旨在比较 80 微米 LASIK 与 100 微米 LASIK 在治疗近视和近视散光中的安全性、有效性和视觉效果。该研究在印度北部的一家三级保健医院进行。

方法

这是一项前瞻性的对照眼研究,纳入了寻求屈光矫正的近视和近视散光患者。入选标准包括正常角膜地形,上皮厚度小于 60 微米,计算的组织消融百分比(用 100 微米瓣)小于 40%,计算的剩余基质床厚度(用 100 微米瓣)大于 300 微米,以及愿意参与和随访。排除青光眼、白内障、其他致盲性眼病变和既往眼手术史的患者。所有患者均接受 80 微米 LASIK 一只眼和 100 微米 LASIK 另一只眼治疗。患者随访 6 个月,分析结果。

结果

该研究纳入了 108 例患者的 216 只眼。80 微米组和 100 微米组术前平均等效球镜分别为-3.53 ± 1.81 和-3.69 ± 1.32 屈光度(P = 0.78)。80 微米组和 100 微米组术后 6 个月十进制最佳矫正视力(UCVA)分别为 0.98 ± 0.13 和 0.97 ± 0.14(P = 0.99)。两组术后高阶像差谱的变化相似(P = 0.78)。80 微米组组织消融百分比明显较低(P = 0.002)。80 微米组瓣微条纹和 OBL 的发生率较高,但这些都没有任何视觉影响。

结论

该研究得出结论,80 微米 LASIK 是 100 微米 LASIK 的有效且安全的替代方案,尤其是对高度近视患者更为有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdcc/11552802/aef22befaa92/IJO-72-1308-g001.jpg

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