骨膜蒂移植作为引导组织再生屏障膜的临床疗效：一项系统评价和荟萃分析。

Clinical efficacy of periosteal pedicle graft as a barrier membrane in guided tissue regeneration: A systematic review and meta-analysis.

作者信息

Iyer Shraddha, Sidharthan Sangamithra, Gopalakrishnan Dharmarajan, Mehta Vini, Chetana Chetana, Guruprasad Meghana, Killedar Sharvari

机构信息

Department of Periodontology, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.

Department of Public Health Dentistry, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India.

出版信息

Dent Res J (Isfahan). 2024 Jul 12;21:37. eCollection 2024.

PMID:39188392

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11346614/

Abstract

BACKGROUND

The study aims to assess the clinical efficacy of periosteal pedicle graft (PPG) as a barrier membrane in guided tissue regeneration (GTR) for gingival recession, intrabony, and furcation defects.

MATERIALS AND METHODS

Electronic and hand searches were performed to identify randomized controlled/clinical trials investigating GTR using PPG, with 6-month follow-up. Primary outcomes recorded: probing depth (PD), clinical attachment level (CAL), bone fill, recession depth (RD) reduction, percentage of mean root coverage, keratinized tissue width (KTW), and bone defect area (BDA).

RESULTS

Thirteen articles were selected; 6 for recession, 2 for furcation, and 5 for intrabony. Meta-analysis was performed whenever possible, results expressed as pooled standardized mean differences (SMDs). In recession defects, the RD pooled SMD is 0.47 (95% confidence interval (CI) = [-0.50-1.44]), KTW pooled SMD is 1.30 (95% CI = [-0.30-2.91]), favoring PPG over the comparator. In furcation defects, PD pooled SMD is 1.12 (95% CI = [-2.77-0.52]), CAL pooled SMD is 0.71 (95% CI = [-1.09-2.50]), and bone fill pooled SMD is 0.67 (95% CI = [-3.34-4.69]) favoring PPG. In intrabony defects, PD pooled SMD is 0.54 (95% CI = [-2.12-1.04]), CAL pooled SMD is 0.23 (95% CI = [-1.13-0.68]), and BDA pooled SMD is 0.37 (95% CI = [-1.58-2.31]) favoring PPG. The results were not statistically significant.

CONCLUSION

The current evidence indicates that PPG constitutes a valid and reliable alternative to collagen barrier membranes for successful GTR.

摘要

背景

本研究旨在评估骨膜蒂移植（PPG）作为引导组织再生（GTR）中用于牙龈退缩、骨内和根分叉缺损的屏障膜的临床疗效。

材料与方法

进行电子检索和手工检索，以识别使用PPG进行GTR并随访6个月的随机对照/临床试验。记录的主要结局指标：探诊深度（PD）、临床附着水平（CAL）、骨填充、退缩深度（RD）减少、平均根覆盖百分比、角化组织宽度（KTW）和骨缺损面积（BDA）。

结果

共筛选出13篇文章；6篇用于牙龈退缩，2篇用于根分叉，5篇用于骨内缺损。尽可能进行荟萃分析，结果以合并标准化均值差（SMD）表示。在牙龈退缩缺损中，RD合并SMD为0.47（95%置信区间（CI）=[-0.50 - 1.44]），KTW合并SMD为1.30（95%CI=[-0.30 - 2.91]），PPG优于对照。在根分叉缺损中，PD合并SMD为1.12（95%CI=[-2.77 - 0.52]），CAL合并SMD为0.71（95%CI=[-1.09 - 2.50]），骨填充合并SMD为0.67（95%CI=[-3.34 - 4.69]），PPG更具优势。在骨内缺损中，PD合并SMD为0.54（95%CI=[-2.12 - 1.04]），CAL合并SMD为0.23（95%CI=[-1.13 - 0.68]），BDA合并SMD为0.37（95%CI=[-1.58 - 2.31]），PPG更具优势。结果无统计学意义。