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本文引用的文献

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A Noise-Robust Heart Sound Segmentation Algorithm Based on Shannon Energy.一种基于香农能量的抗噪声心音分割算法。
IEEE Access. 2024;12:7747-7761. doi: 10.1109/access.2024.3351570. Epub 2024 Jan 8.
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Identification of Congenital Valvular Murmurs in Young Patients Using Deep Learning-Based Attention Transformers and Phonocardiograms.使用基于深度学习的注意力转换器和心音图识别年轻患者的先天性瓣膜杂音。
IEEE J Biomed Health Inform. 2024 Apr;28(4):1803-1814. doi: 10.1109/JBHI.2024.3357506. Epub 2024 Apr 4.
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Cardiac murmur grading and risk analysis of cardiac diseases based on adaptable heterogeneous-modality multi-task learning.基于自适应异构模态多任务学习的心脏杂音分级与心脏病风险分析。
Health Inf Sci Syst. 2023 Dec 1;12(1):2. doi: 10.1007/s13755-023-00249-4. eCollection 2024 Dec.
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Neural decoding of inferior colliculus multiunit activity for sound category identification with temporal correlation and transfer learning.利用时间相关性和迁移学习对下丘多单位活动进行神经解码以识别声音类别
Network. 2024 May;35(2):101-133. doi: 10.1080/0954898X.2023.2282576. Epub 2023 Nov 20.
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Markov-Based Neural Networks for Heart Sound Segmentation: Using Domain Knowledge in a Principled Way.基于马尔可夫的神经网络在心脏音分割中的应用:在有原则的基础上使用领域知识。
IEEE J Biomed Health Inform. 2023 Nov;27(11):5357-5368. doi: 10.1109/JBHI.2023.3312597. Epub 2023 Nov 7.
6
Beyond Heart Murmur Detection: Automatic Murmur Grading From Phonocardiogram.超越心脏杂音检测:心音图自动杂音分级。
IEEE J Biomed Health Inform. 2023 Aug;27(8):3856-3866. doi: 10.1109/JBHI.2023.3275039. Epub 2023 Aug 8.
7
An Optimal Approach for Heart Sound Classification Using Grid Search in Hyperparameter Optimization of Machine Learning.一种在机器学习超参数优化中使用网格搜索进行心音分类的优化方法。
Bioengineering (Basel). 2022 Dec 29;10(1):45. doi: 10.3390/bioengineering10010045.
8
Explainable AI for clinical and remote health applications: a survey on tabular and time series data.用于临床和远程健康应用的可解释人工智能:关于表格数据和时间序列数据的综述
Artif Intell Rev. 2023;56(6):5261-5315. doi: 10.1007/s10462-022-10304-3. Epub 2022 Oct 26.
9
Application of explainable artificial intelligence for healthcare: A systematic review of the last decade (2011-2022).可解释人工智能在医疗保健中的应用:过去十年(2011-2022 年)的系统回顾。
Comput Methods Programs Biomed. 2022 Nov;226:107161. doi: 10.1016/j.cmpb.2022.107161. Epub 2022 Sep 27.
10
Transfer Learning Models for Detecting Six Categories of Phonocardiogram Recordings.用于检测六类心音图记录的迁移学习模型。
J Cardiovasc Dev Dis. 2022 Mar 16;9(3):86. doi: 10.3390/jcdd9030086.

利用心音图、迁移学习和可解释人工智能快速检测和解读心脏杂音。

Rapid detection and interpretation of heart murmurs using phonocardiograms, transfer learning and explainable artificial intelligence.

作者信息

Özcan Fatma

机构信息

Biophysics Department in Faculty of Medicine, Kahramanmaras Sutcu Imam University, 46100 Kahramanmaras, Turkey.

出版信息

Health Inf Sci Syst. 2024 Aug 24;12(1):43. doi: 10.1007/s13755-024-00302-w. eCollection 2024 Dec.

DOI:10.1007/s13755-024-00302-w
PMID:39188905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11344737/
Abstract

Cardiovascular disease, which remains one of the main causes of death, can be prevented by early diagnosis of heart sounds. Certain noisy signals, known as murmurs, may be present in heart sounds. On auscultation, the degree of murmur is closely related to the patient's clinical condition. Computer-aided decision-making systems can help doctors to detect murmurs and make faster decisions. The Mel spectrograms were generated from raw phonocardiograms and then presented to the OpenL3 network for transfer learning. In this way, the signals were classified to predict the presence or absence of murmurs and their level of severity. Pitch level (healthy, low, medium, high) and Levine scale (healthy, soft, loud) were used. The results obtained without prior segmentation are very impressive. The model used was then interpreted using an Explainable Artificial Intelligence (XAI) method, Occlusion Sensitivity. This approach shows that XAI methods are necessary to know the features used internally by the artificial neural network then to explain the automatic decision taken by the model. The averaged image of the occlusion sensitivity maps can give us either an overview or a precise detail per pixel of the features used. In the field of healthcare, particularly cardiology, for rapid diagnostic and preventive purposes, this work could provide more detail on the important features of the phonocardiogram.

摘要

心血管疾病仍然是主要死因之一,通过早期诊断心音可以预防。心音中可能存在某些被称为杂音的嘈杂信号。听诊时,杂音的程度与患者的临床状况密切相关。计算机辅助决策系统可以帮助医生检测杂音并更快地做出决策。梅尔频谱图由原始心音图生成,然后呈现给OpenL3网络进行迁移学习。通过这种方式,对信号进行分类以预测杂音的有无及其严重程度。使用了音高等级(正常、低、中、高)和莱文分级(正常、柔和、响亮)。在没有预先分割的情况下获得的结果非常令人印象深刻。然后使用可解释人工智能(XAI)方法——遮挡敏感度对所使用的模型进行解释。这种方法表明,XAI方法对于了解人工神经网络内部使用的特征然后解释模型做出的自动决策是必要的。遮挡敏感度图的平均图像可以为我们提供所使用特征的总体概述或每个像素的精确细节。在医疗保健领域,特别是心脏病学领域,为了快速诊断和预防目的,这项工作可以提供有关心音图重要特征的更多细节。