Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
Department of Laboratory Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China.
Analyst. 2024 Oct 7;149(20):5034-5040. doi: 10.1039/d4an00977k.
Dielectric barrier discharge ionization is increasingly used for rapid detection in ambient mass spectrometry, although more often for gaseous and highly volatile samples than for solids and liquids. In this project, we present a rapid and sensitive method for detecting mycotoxins and demonstrate its capability for the detection of aflatoxin B1, zearalenone, and ochratoxin A in food samples. Our method is based on thermal desorption coupled to dielectric barrier discharge ionization mass spectrometry (TD-DBDI-MS), which we show generates minimal interferences and produces almost exclusively molecular ions. We detected mycotoxins in various food samples, including corn, peanuts, millet, and rice. Our method has a linear dynamic range of 1 μg kg to 100 μg kg for all three mycotoxins and a limit of detection (LOD) of 0.31 μg kg, 0.28 μg kg and 0.43 μg kg, respectively. It is simple, rapid, reduces the pretreatment steps and has significant potential for practical applications.
介质阻挡放电电离越来越多地用于环境质谱中的快速检测，尽管它更常用于气态和高挥发性样品，而不是用于固体和液体。在这个项目中，我们提出了一种快速灵敏的检测霉菌毒素的方法，并证明了它在检测食品样品中的黄曲霉毒素 B1、玉米赤霉烯酮和赭曲霉毒素 A 的能力。我们的方法基于热解吸耦合介质阻挡放电电离质谱（TD-DBDI-MS），我们证明它产生的干扰最小，并几乎只产生分子离子。我们在各种食品样品中检测到了霉菌毒素，包括玉米、花生、小米和大米。我们的方法对所有三种霉菌毒素的线性动态范围为 1 μg kg 至 100 μg kg，检测限（LOD）分别为 0.31 μg kg、0.28 μg kg 和 0.43 μg kg。它简单、快速，减少了预处理步骤，具有很大的实际应用潜力。
