Revathi Seemaisamy, Altemimi Ammar B, Sutikno Sutikno, Cacciola Francesco
Research Center for Applied Zoology, Research Organization for Life Science and Environment, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Food Science Department, College of Agriculture, University of Basrah, Basrah, Iraq.
Int J Environ Health Res. 2025 Jun;35(6):1557-1570. doi: 10.1080/09603123.2024.2395446. Epub 2024 Aug 27.
This study aimed to evaluate the phytochemical content and biological properties of (L.) Roxb. Four extracts-acetone, methanol, ethanol, and chloroform-were tested for antioxidant potential, enzymatic activity (peroxidase and polyphenol oxidase), antimicrobial, and anticancer effects. GC-MS analysis identified 34 bioactive compounds. The acetone extract exhibited the highest total alkaloid (5.8%), phenolic (752.78 ± 2.25 mg GAE/g), and flavonoid (285.78 ± 1.25 mg QE/g) content, along with the highest antioxidant (1489.42 ± 4.35 mg AAE/g) and enzyme activities. All extracts inhibited both Gram-positive and negative bacteria, with the acetone extract showing superior inhibition against and . Additionally, the acetone and methanol extracts demonstrated anticancer effects on MDA-MB-231 breast cancer cells. These findings suggest that has potential as a therapeutic agent for various diseases.
本研究旨在评估（此处植物拉丁名缺失）的植物化学成分和生物学特性。对四种提取物——丙酮提取物、甲醇提取物、乙醇提取物和氯仿提取物——进行了抗氧化潜力、酶活性（过氧化物酶和多酚氧化酶）、抗菌和抗癌作用的测试。气相色谱-质谱联用（GC-MS）分析鉴定出34种生物活性化合物。丙酮提取物的总生物碱含量最高（5.8%）、酚类含量最高（752.78 ± 2.25毫克没食子酸当量/克）、黄酮类含量最高（285.78 ± 1.25毫克槲皮素当量/克），同时具有最高的抗氧化活性（1489.42 ± 4.35毫克抗坏血酸当量/克）和酶活性。所有提取物均能抑制革兰氏阳性菌和阴性菌，其中丙酮提取物对（此处细菌名称缺失）和（此处细菌名称缺失）表现出更强的抑制作用。此外，丙酮提取物和甲醇提取物对MDA-MB-231乳腺癌细胞具有抗癌作用。这些发现表明（此处植物名称缺失）具有作为多种疾病治疗剂的潜力。
