Jequier A M, Ansell I D, Bullimore N J
J Androl. 1985 Jan-Feb;6(1):15-9.
Congenital absence of both vasa deferentia is not an infrequent cause of sterility. Between April 1975 and December 1981, 11 men out of a total of 749 presenting with infertility were diagnosed as having congenital absence of both vasa deferentia. Subsequent clinical investigations showed that FSH levels were within the normal range (2-10 mIU/ml), blood karyotype (XY) was normal, and testicular histology demonstrated normal spermatogenesis. Seminal volume was markedly reduced in nine patients (range 0.25-1.0 ml). In three out of four patients tested, seminal fructose was found to be completely absent. Of the 11 patients, eight subsequently had exploratory surgery. In four men, the whole epididymis was present on both sides, while the other four had varying parts of one or both epididymides absent. In six of the eight patients explored surgically, no trace of the vasa deferentia could be found, while one other patient had thin fibrous cords in the anatomical site of the vasa deferentia. A possible cause for the abnormality and the importance of seminal fructose estimation are discussed.
双侧输精管先天性缺如并非不育的罕见原因。1975年4月至1981年12月期间，在749例因不育前来就诊的男性中，有11例被诊断为双侧输精管先天性缺如。随后的临床检查显示，促卵泡生成素（FSH）水平在正常范围内（2 - 10 mIU/ml），血液核型（XY）正常，睾丸组织学显示生精功能正常。9例患者的精液量显著减少（范围为0.25 - 1.0 ml）。在接受检测的4例患者中，有3例精液中完全没有果糖。11例患者中有8例随后接受了探查手术。4例男性双侧附睾完整，而另外4例患者一侧或双侧附睾的不同部位缺如。在接受手术探查的8例患者中，有6例未发现输精管的踪迹，而另1例患者在输精管的解剖部位有纤细的纤维索。本文讨论了该异常情况的可能原因以及精液果糖测定的重要性。
