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淋病奈瑟菌中DNA的III型5-甲基胞嘧啶修饰

Type III 5-methylcytosine modification of DNA in Neisseria gonorrhoeae.

作者信息

Korch C, Hagblom P, Normark S

出版信息

J Bacteriol. 1985 Mar;161(3):1236-7. doi: 10.1128/jb.161.3.1236-1237.1985.

DOI:10.1128/jb.161.3.1236-1237.1985
PMID:3918988
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC215036/
Abstract

We present here the first report of a type III methyltransferase that modifies a cytosine. Neisseria gonorrhoeae 82409/55 (pJD1) modifies the first cytosine on only one strand from the 5' end of the nonpalindromic sequence: (Formula; see text). We have called this modifying activity M X NgoVIII.

摘要

我们在此展示了一种修饰胞嘧啶的III型甲基转移酶的首次报道。淋病奈瑟菌82409/55（pJD1）仅在非回文序列5'端的一条链上修饰第一个胞嘧啶：（公式；见正文）。我们将这种修饰活性称为M X NgoVIII。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22cf/215036/153499f88c5d/jbacter00226-0421-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22cf/215036/153499f88c5d/jbacter00226-0421-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22cf/215036/153499f88c5d/jbacter00226-0421-a.jpg

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引用本文的文献

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本文引用的文献

1
Sequence-specific DNA modification in Neisseria gonorrhoeae.淋病奈瑟菌中的序列特异性DNA修饰
J Bacteriol. 1983 Sep;155(3):1324-32. doi: 10.1128/jb.155.3.1324-1332.1983.
2
Restriction and modification enzymes and their recognition sequences.限制酶和修饰酶及其识别序列。
Nucleic Acids Res. 1983 Jan 11;11(1):r135-67.
3
Structure and mechanism of multifunctional restriction endonucleases.多功能限制性核酸内切酶的结构与机制
淋病奈瑟菌的隐蔽质粒：完整核苷酸序列及基因组织
J Bacteriol. 1985 Aug;163(2):430-8. doi: 10.1128/jb.163.2.430-438.1985.
4
Restriction of plasmid DNA during transformation but not conjugation in Neisseria gonorrhoeae.淋病奈瑟菌转化过程中质粒DNA受到限制，但在接合过程中不受限制。
Infect Immun. 1988 Jan;56(1):112-6. doi: 10.1128/iai.56.1.112-116.1988.
5
Restriction enzymes and their isoschizomers.限制性内切酶及其同裂酶。
Nucleic Acids Res. 1989;17 Suppl(Suppl):r347-87. doi: 10.1093/nar/17.suppl.r347.
6
DNA restriction and modification systems in Neisseria gonorrhoeae.淋病奈瑟菌中的DNA限制与修饰系统。
Clin Microbiol Rev. 1989 Apr;2 Suppl(Suppl):S78-82. doi: 10.1128/CMR.2.Suppl.S78.
7
High-frequency mobilization of broad-host-range plasmids into Neisseria gonorrhoeae requires methylation in the donor.将广宿主范围质粒高频转移至淋病奈瑟菌需要供体中的甲基化作用。
J Bacteriol. 1991 Sep;173(18):5793-9. doi: 10.1128/jb.173.18.5793-5799.1991.
8
Site-specific methylation: effect on DNA modification methyltransferases and restriction endonucleases.位点特异性甲基化：对DNA修饰甲基转移酶和限制性内切酶的影响。
Nucleic Acids Res. 1991 Apr 25;19 Suppl(Suppl):2045-71. doi: 10.1093/nar/19.suppl.2045.
9
Cloning and linkage analysis of Neisseria gonorrhoeae DNA methyltransferases.淋病奈瑟菌DNA甲基转移酶的克隆与连锁分析。
J Bacteriol. 1992 Sep;174(17):5654-60. doi: 10.1128/jb.174.17.5654-5660.1992.
10
Construction of a Neisseria gonorrhoeae MS11 derivative deficient in NgoMI restriction and modification.构建缺乏NgoMI限制与修饰功能的淋病奈瑟菌MS11衍生物。
J Bacteriol. 1992 Aug;174(15):4899-906. doi: 10.1128/jb.174.15.4899-4906.1992.
Annu Rev Biochem. 1981;50:285-319. doi: 10.1146/annurev.bi.50.070181.001441.
4
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Methods Enzymol. 1980;65(1):499-560. doi: 10.1016/s0076-6879(80)65059-9.
6
Detection of 5-methylcytosine in DNA sequences.DNA序列中5-甲基胞嘧啶的检测。
Nucleic Acids Res. 1978 May;5(5):1479-85. doi: 10.1093/nar/5.5.1479.