Sun Jinghui, Tong Hao, Yan Yifei, Huang Zhiwei, Chen Xuanxuan, Huang Yinhua
College of Materials, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou 311121, China.
Org Lett. 2024 Sep 6;26(35):7414-7418. doi: 10.1021/acs.orglett.4c02747. Epub 2024 Aug 27.
An efficient copper-promoted divergent phosphination of alkynylsulfonium salts with secondary diarylphosphines that tolerates a wide range of functional groups under mild conditions is reported. The use of excess alkynyl dibenzothiophenium salts (/ > 1, mole ratio) enables the phosphination to deliver alkynyl monophosphine products via a C(sp)-P cross-coupling in good to high yields, while the use of excess secondary diarylphosphines (/ < 0.5, mole ratio) leads to a type of -ethenyl bisphosphine products via sequential stereoselective double phosphination.
