Ye Yun, Zhu Jie, Huang Yinhua
College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 311121, China.
Org Lett. 2021 Mar 19;23(6):2386-2391. doi: 10.1021/acs.orglett.1c00748. Epub 2021 Mar 10.
Diverse C-P cross-couplings of arylthianthrenium salts with diarylphosphines producing various triarylphosphines via highly selective C-S bond cleavage are reported. In the absence of catalyst, the reaction of arylthianthrenium salts with diarylphosphines undergoes phosphinative ring opening exclusively via the cleavage of an endocyclic C-S bond of a thianthrene skeleton. The use of a palladacycle catalyst under otherwise the same conditions enables the phosphination via the cleavage of an exocyclic C-S bond with significantly higher speed.
报道了芳基噻蒽鎓盐与二芳基膦的多种C-P交叉偶联反应，通过高度选择性的C-S键裂解生成各种三芳基膦。在没有催化剂的情况下，芳基噻蒽鎓盐与二芳基膦的反应仅通过噻蒽骨架的内环C-S键裂解进行膦化开环反应。在其他条件相同的情况下，使用钯环催化剂能够通过外环C-S键的裂解以显著更高的速度进行膦化反应。
