No information is available on the clinical use of galsulfase during breastfeeding. Because it is a large protein molecule with a molecular weight of about 56,000 Da, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. If the mother requires galsulfase, it is not a reason to discontinue breastfeeding. Until more data are available, use galsulfase with infant careful monitoring during breastfeeding.
关于哺乳期使用加硫酶的临床应用尚无可用信息。由于它是一种分子量约为56,000道尔顿的大蛋白质分子,乳汁中的含量可能非常低,而且由于它可能会在婴儿胃肠道中被破坏,不太可能被吸收。如果母亲需要使用加硫酶,这并不是停止母乳喂养的理由。在获得更多数据之前,哺乳期使用加硫酶时需对婴儿进行密切监测。