No information is available on the clinical use of elosulfase alfa during breastfeeding. Because it is a large protein molecule with a molecular weight of about 55,000 Da, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. If elosulfase alfa is required by the mother, it is not a reason to discontinue breastfeeding. Until more data are available, elosulfase alfa should be used with infant careful monitoring during breastfeeding.
关于在母乳喂养期间使用阿加糖酶α的临床信息尚无可用资料。由于它是一种分子量约为55,000道尔顿的大蛋白质分子,乳汁中的含量可能非常低,而且由于其可能在婴儿胃肠道中被破坏,吸收的可能性不大。如果母亲需要使用阿加糖酶α,这并非停止母乳喂养的理由。在获得更多数据之前,母乳喂养期间使用阿加糖酶α时应对婴儿进行仔细监测。