No information is available on the clinical use of vestronidase alfa during breastfeeding. Because vestronidase alfa is a large protein molecule with a molecular weight of about 290,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. If vestronidase alfa is required by the mother, it is not a reason to discontinue breastfeeding. Until more data are available, vestronidase alfa should be used with careful infant monitoring during breastfeeding.
目前尚无关于维司妥昔单抗α在母乳喂养期间临床应用的信息。由于维司妥昔单抗α是一种分子量约为290,000的大分子蛋白质,其在乳汁中的含量可能非常低,而且由于它可能会在婴儿胃肠道中被破坏,所以不太可能被吸收。如果母亲需要使用维司妥昔单抗α,这并不是停止母乳喂养的理由。在获得更多数据之前,母乳喂养期间使用维司妥昔单抗α时应仔细监测婴儿情况。