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韩国 2 型糖尿病的患病率、知晓率、治疗率和控制率(1998 年至 2022 年):全国性横断面研究。

Prevalence, Awareness, Treatment, and Control of Type 2 Diabetes in South Korea (1998 to 2022): Nationwide Cross-Sectional Study.

机构信息

Department of Medicine, Kyung Hee University College of Medicine, Seoul, Republic of Korea.

Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, Republic of Korea.

出版信息

JMIR Public Health Surveill. 2024 Aug 27;10:e59571. doi: 10.2196/59571.

Abstract

BACKGROUND

Type 2 diabetes poses an increasing disease burden in South Korea. The development and management of type 2 diabetes are closely related to lifestyle and socioeconomic factors, which have undergone substantial changes over the past few decades, including during the COVID-19 pandemic.

OBJECTIVE

This study aimed to investigate long-term trends in type 2 diabetes prevalence, awareness, treatment, and control. It also aimed to determine whether there were substantial alterations in the trends during the pandemic and whether these changes were more pronounced within specific demographic groups.

METHODS

This study examined the prevalence, awareness, treatment, and control of type 2 diabetes in a representative sample of 139,786 South Koreans aged >30 years, using data from the National Health and Nutrition Examination Survey and covering the period from 1998 to 2022. Weighted linear regression and binary logistic regression were performed to calculate weighted β coefficients or odds ratios. Stratified analyses were performed based on sex, age, region of residence, obesity status, educational background, household income, and smoking status. β (difference) was calculated to analyze the trend difference between the prepandemic period and the COVID-19 pandemic. To identify groups more susceptible to type 2 diabetes, we estimated interaction terms for each factor and calculated weighted odds ratios.

RESULTS

From 1998 to 2022, a consistent increase in the prevalence of type 2 diabetes was observed among South Koreans, with a notable rise to 15.61% (95% CI 14.83-16.38) during the pandemic. Awareness followed a U-shaped curve, bottoming out at 64.37% (95% CI 61.79-66.96) from 2013 to 2015 before increasing to 72.56% (95% CI 70.39-74.72) during the pandemic. Treatment also increased over time, peaking at 68.33% (95% CI 65.95-70.71) during the pandemic. Control among participants with diabetes showed no substantial change, maintaining a rate of 29.14% (95% CI 26.82-31.47) from 2020 to 2022, while control among treated participants improved to 30.68% (95% CI 27.88-33.48). During the pandemic, there was a steepening of the curves for awareness and treatment. However, while the slope of control among participants being treated increased, the slope of control among participants with diabetes showed no substantial change during the pandemic. Older populations and individuals with lower educational level exhibited less improvement in awareness and control trends than younger populations and more educated individuals. People with lower income experienced a deceleration in prevalence during the pandemic.

CONCLUSIONS

Over the recent decade, there has been an increase in type 2 diabetes prevalence, awareness, treatment, and control. During the pandemic, a steeper increase in awareness, treatment, and control among participants being treated was observed. However, there were heterogeneous changes across different population groups, underscoring the need for targeted interventions to address disparities and improve diabetes management for susceptible populations.

摘要

背景

2 型糖尿病在韩国的疾病负担日益加重。2 型糖尿病的发生和管理与生活方式和社会经济因素密切相关,这些因素在过去几十年中发生了重大变化,包括在 COVID-19 大流行期间。

目的

本研究旨在调查 2 型糖尿病患病率、知晓率、治疗率和控制率的长期趋势。还旨在确定在大流行期间是否存在趋势的重大变化,以及这些变化在特定人群中是否更为明显。

方法

本研究使用了来自韩国全国健康和营养检查调查的年龄在 30 岁以上的 139786 名韩国人的代表性样本,研究了 2 型糖尿病的患病率、知晓率、治疗率和控制率。从 1998 年到 2022 年,使用加权线性回归和二项逻辑回归计算了加权β系数或比值比。基于性别、年龄、居住地区、肥胖状况、教育背景、家庭收入和吸烟状况进行了分层分析。计算差异β值来分析大流行前和 COVID-19 大流行期间的趋势差异。为了确定更容易患 2 型糖尿病的人群,我们为每个因素估计了交互项,并计算了加权比值比。

结果

从 1998 年到 2022 年,韩国人 2 型糖尿病的患病率持续上升,在大流行期间显著上升至 15.61%(95%CI 14.83-16.38)。知晓率呈 U 形曲线,在 2013 年至 2015 年期间达到 64.37%(95%CI 61.79-66.96)的最低点,然后在大流行期间上升至 72.56%(95%CI 70.39-74.72)。治疗率也随时间推移而增加,在大流行期间达到 68.33%(95%CI 65.95-70.71)的峰值。糖尿病患者的控制率没有明显变化,从 2020 年至 2022 年保持在 29.14%(95%CI 26.82-31.47),而接受治疗的患者的控制率提高至 30.68%(95%CI 27.88-33.48)。在大流行期间,知晓率和治疗率的曲线变得更加陡峭。然而,尽管接受治疗的患者的控制率斜率有所增加,但糖尿病患者的控制率斜率在大流行期间没有明显变化。年龄较大的人群和受教育程度较低的人群在知晓率和控制率趋势方面的改善程度低于年龄较小的人群和受教育程度较高的人群。收入较低的人群在大流行期间患病率有所下降。

结论

在最近十年中,2 型糖尿病的患病率、知晓率、治疗率和控制率都有所增加。在大流行期间,接受治疗的患者的知晓率、治疗率和控制率呈更陡峭的上升趋势。然而,不同人群群体之间存在不均匀的变化,这突显了需要采取有针对性的干预措施,以解决易感人群的差异,并改善糖尿病管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/627a/11387923/10c2376c72ac/publichealth_v10i1e59571_fig1.jpg

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