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骨水泥固定:经皮椎体后凸成形术相关肺水泥栓塞:一例报告。

Cemented in place: kyphoplasty-associated pulmonary cement embolism: a case report.

机构信息

University of Minnesota Medical School, Minneapolis, MN, USA.

Internal Medicine Residency, University of Minnesota Medical School, Minneapolis, MN, USA.

出版信息

J Med Case Rep. 2024 Aug 28;18(1):407. doi: 10.1186/s13256-024-04656-3.

Abstract

BACKGROUND

Kyphoplasty-associated cement extravasation into surrounding tissue and vasculature can lead to life-threatening complications. We present a rare case of significant inferior vena cava cement burden that resulted in pulmonary embolism.

CASE PRESENTATION

A 74-year-old Caucasian woman with a history of severe osteoporosis, recurrent falls, and spinal compression fracture status post-kyphoplasty of the L4-L5 vertebrae, presents to the emergency department 2 days post-vertebral kyphoplasty due to chest pain, back pain, and dyspnea. Computed tomography of the chest and abdomen showed a metallic density within the inferior vena cava extending superiorly approximately 10 cm from the vertebral L5 level. She was also found to have right lower lobe pneumonia. The patient finished a 10-day course of antibiotics and was discharged home with a 1-month long course of anticoagulation with apixaban per recommendations of a multidisciplinary team consisting of Hematology/Oncology, Interventional Radiology, Vascular Surgery, and Orthopedic Surgery. Unfortunately, the patient was readmitted a month later with shortness of breath. Work up was notable for an influenza type A infection and computed tomography findings of pulmonary cement embolism. The respiratory distress was resolved with supportive care. Despite pulmonary cement burden, the multidisciplinary care team recommended no further anticoagulation. Patient was discharged home with close clinical follow-up and 6 months has since passed at the time of this report without reported complications.

CONCLUSIONS

A large cement burden in the inferior vena cava leading to pulmonary cement embolism is a rare event. A high burden of cement predisposes development of pulmonary embolism. A short course of anticoagulation may only be needed for asymptomatic patients.

摘要

背景

球囊扩张椎体后凸成形术相关的水泥向周围组织和脉管系统外渗可导致危及生命的并发症。我们报告了一例罕见的严重下腔静脉水泥负荷导致肺栓塞的病例。

病例介绍

一位 74 岁白人女性,有严重骨质疏松症、反复跌倒和脊柱压缩性骨折病史,曾接受 L4-L5 椎体的球囊扩张椎体后凸成形术,术后 2 天因胸痛、背痛和呼吸困难就诊于急诊科。胸部和腹部计算机断层扫描显示下腔静脉内存在金属密度物质,从 L5 椎体水平向上延伸约 10cm。她还被发现患有右下肺肺炎。患者接受了为期 10 天的抗生素治疗,随后根据血液科/肿瘤学、介入放射科、血管外科和骨科多学科团队的建议,接受为期 1 个月的阿哌沙班抗凝治疗出院。不幸的是,一个月后患者因呼吸急促再次入院。检查结果显示甲型流感感染和计算机断层扫描发现肺水泥栓塞。通过支持性治疗缓解了呼吸窘迫。尽管存在肺水泥负荷,多学科护理团队建议不再进行抗凝治疗。患者出院回家,密切临床随访,自报告时起已过去 6 个月,无报告并发症。

结论

下腔静脉内大量水泥负荷导致肺水泥栓塞是一种罕见事件。大量水泥负荷可导致肺栓塞的发生。对于无症状患者,可能仅需要短期抗凝治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9218/11350933/d257fe53e2c3/13256_2024_4656_Fig1_HTML.jpg

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