Sinikumpu Suvi-Päivikki, Jokelainen Jari, Auvinen Juha, Timonen Markku, Huilaja Laura
Department of Dermatology, Oulu University Hospital, Oulu, Finland
PEDEGO Research Group, Medical Research Center, University of Oulu, Oulu, Pohjois-Pohjanmaa, Finland.
BMJ Open. 2021 Dec 30;11(12):e049855. doi: 10.1136/bmjopen-2021-049855.
To study the association between androgenetic alopecia (AGA) and its severity with psychosocial well-being in male subjects aged 46 years at the population level.
Cross-sectional study.
The Northern Finland Birth Cohort 1966 (NFBC1966).
Data were available for 892 male subjects aged 46 years.
Study subjects underwent comprehensive health examinations including a skin evaluation by dermatologists and determination of AGA according to the Norwood classification. They also filled in a questionnaire battery that included previously validated questionnaires: the Hopkins Symptom Checklist-25, the Beck Depression Inventory-II; the Generalised Anxiety Disorder Screener; a 15-dimensional measure of health-related quality of life; a 12-Item General Health Questionnaire. The battery also included questions about self-esteem and sexual health.
The presence of AGA and its severity, psychosocial well-being.
AGA was found in 68.5% of subjects, 27.8% of the cases were severe, 33.2% moderate and 39.0% mild. There was no significant association between the presence of AGA or its severity with depression, anxiety, quality of life, self-esteem or sexual symptoms. Those with severe AGA reported lower sexual activity when compared with those without AGA; however, the difference was not statistically significant.
Middle-aged men with AGA did not differ from men without AGA in terms of psychosocial well-being.
在人群层面研究46岁男性雄激素性脱发(AGA)及其严重程度与心理社会幸福感之间的关联。
横断面研究。
1966年芬兰北部出生队列(NFBC1966)。
892名46岁男性的资料可供分析。
研究对象接受了全面的健康检查,包括皮肤科医生进行的皮肤评估以及根据诺伍德分类法确定雄激素性脱发情况。他们还填写了一系列问卷,其中包括先前经验证有效的问卷:《霍普金斯症状清单-25》、《贝克抑郁量表第二版》、《广泛性焦虑症筛查量表》、一项15维度的健康相关生活质量测量量表、《12项一般健康问卷》。该问卷系列还包括有关自尊和性健康的问题。
雄激素性脱发的存在及其严重程度、心理社会幸福感。
68.5%的研究对象存在雄激素性脱发,其中27.8%为重度,33.2%为中度,39.0%为轻度。雄激素性脱发的存在或其严重程度与抑郁、焦虑、生活质量、自尊或性症状之间无显著关联。与无雄激素性脱发者相比,重度雄激素性脱发者报告的性活动较少;然而,差异无统计学意义。
在心理社会幸福感方面,患有雄激素性脱发的中年男性与未患雄激素性脱发的男性没有差异。