Rozman Ales, Grabczak Elzbieta Magdalena, George Vineeth, Marc Malovrh Mateja, Novais Bastos Helder, Trojnar Anna, Graffen Simon, Tenda Eric Daniel, Hardavella Georgia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia.
Breathe (Sheff). 2024 Aug 27;20(2):230201. doi: 10.1183/20734735.0201-2023. eCollection 2024 Jun.
Interventional bronchoscopy has seen significant advancements in recent decades, particularly in the context of lung cancer. This method has expanded not only diagnostic capabilities but also therapeutic options. In this article, we will outline various therapeutic approaches employed through either a rigid or flexible bronchoscope in multimodal lung cancer treatment. A pivotal focus lies in addressing central airway obstruction resulting from cancer. We will delve into the treatment of initial malignant changes in central airways and explore the rapidly evolving domain of early peripheral malignant lesions, increasingly discovered incidentally or through lung cancer screening programmes. A successful interventional bronchoscopic procedure not only alleviates severe symptoms but also enhances the patient's functional status, paving the way for subsequent multimodal treatments and thereby extending the possibilities for survival. Interventional bronchoscopy proves effective in treating initial cancerous changes in patients unsuitable for surgical or other aggressive treatments due to accompanying diseases. The key advantage of interventional bronchoscopy lies in its minimal invasiveness, effectiveness and favourable safety profile.
近几十年来，介入性支气管镜检查取得了显著进展，尤其是在肺癌治疗方面。这种方法不仅扩大了诊断能力，还增加了治疗选择。在本文中，我们将概述在多模式肺癌治疗中通过硬支气管镜或软支气管镜采用的各种治疗方法。一个关键重点在于解决癌症导致的中央气道阻塞问题。我们将深入探讨中央气道初始恶性病变的治疗，并探索早期外周恶性病变这一迅速发展的领域，这些病变越来越多地通过偶然发现或肺癌筛查计划被发现。成功的介入性支气管镜检查不仅能缓解严重症状，还能改善患者的功能状态，为后续的多模式治疗铺平道路，从而延长生存可能性。对于因伴随疾病而不适合手术或其他积极治疗的患者，介入性支气管镜检查在治疗初始癌性病变方面被证明是有效的。介入性支气管镜检查的关键优势在于其微创性、有效性和良好的安全性。
