da Silva Giuliano Roberto, Terra Gerusa Dias Siqueira Vilela, de Oliveira David Michel, Fernandes Eduardo Vignoto, Zechin Emerson José, Soares Arthur Rizzi, Pessoa-Filho Dalton Muller, Neiva Cassiano Merussi
Department of Physical Education, Professor Edson Antônio Velano University, Alfenas 37132-440, Minas Gerais, Brazil.
Postgraduate Program in Animal Bioscience, Federal University of Jataí, Jataí 75801-615, Goiás, Brazil.
Metabolites. 2024 Jul 31;14(8):422. doi: 10.3390/metabo14080422.
Metabolic syndrome (MS) increases the risk of cardiovascular disease and affects children and adolescents. Butyrylcholinesterase (BChE) is an enzyme associated with obesity. The aim of this study was to investigate the effects of different physical training protocols on MS indicators and their relationship with BChE activity. This randomized clinical trial included 80 adolescents randomly assigned to 4 groups (CG: Control Group; ATG: Aerobic Training Group; STG: Strength Training Group; and CTG: Concurrent Training Group). The EFC, lipid profile, glycemia, waist circumference, and blood pressure were analyzed. With the exception of the CG, all the groups underwent training protocols for 12 consecutive weeks, 4 times a week, as follows: (ATG: 75% of heart rate on an electric treadmill; STG: 85% of 1 maximum repetition; CTG: 20 min of aerobic training at the same intensity as the ATG, and 20 min of resistance training in the same way as the STG). The training reduced MS-related biomarkers, such as the lipid profile, glycemia, waist circumference, and blood pressure. STG reduced BChE activity. The training methods led to improvements in the majority of the MS indicators. In addition, aerobic training significantly reduced BChE activity after a 12-week training protocol. The results suggest that different types of exercise can benefit MS.
代谢综合征（MS）会增加心血管疾病风险，且影响儿童和青少年。丁酰胆碱酯酶（BChE）是一种与肥胖相关的酶。本研究旨在探讨不同体育训练方案对MS指标的影响及其与BChE活性的关系。这项随机临床试验纳入了80名青少年，他们被随机分为4组（CG：对照组；ATG：有氧训练组；STG：力量训练组；CTG：联合训练组）。分析了空腹血糖（EFC）、血脂谱、血糖、腰围和血压。除CG组外，所有组连续12周、每周4次进行训练方案，具体如下：（ATG：在电动跑步机上达到心率的75%；STG：1次最大重复量的85%；CTG：与ATG相同强度进行20分钟有氧训练，与STG相同方式进行20分钟抗阻训练）。训练降低了与MS相关的生物标志物，如血脂谱、血糖、腰围和血压。STG组降低了BChE活性。这些训练方法使大多数MS指标得到改善。此外，经过12周训练方案后，有氧训练显著降低了BChE活性。结果表明，不同类型的运动对MS有益。
