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Sweet and sour story of maternal diabetes and birth defects.

作者信息

Steimle Jeffrey D, Martin James F

机构信息

Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA.

Cardiomyocyte Renewal Laboratory, Texas Heart Institute, Houston, TX, USA.

出版信息

Nat Cardiovasc Res. 2023 Dec;2(12):1107-1108. doi: 10.1038/s44161-023-00380-1.

DOI:10.1038/s44161-023-00380-1
PMID:39196143
Abstract
摘要

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Tbx5 drives expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development.Tbx5 驱动表达来调节 RA-Hedgehog-Wnt 基因调控网络，协调心肺发育。
Elife. 2021 Oct 13;10:e69288. doi: 10.7554/eLife.69288.
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Outflow Tract Formation-Embryonic Origins of Conotruncal Congenital Heart Disease.流出道形成——圆锥动脉干先天性心脏病的胚胎起源
J Cardiovasc Dev Dis. 2021 Apr 9;8(4):42. doi: 10.3390/jcdd8040042.
3
Comprehensive assessment of the associations between maternal diabetes and structural birth defects in offspring: a phenome-wide association study.
综合评估母亲糖尿病与后代结构出生缺陷的关联：表型全基因组关联研究。
Ann Epidemiol. 2021 Jan;53:14-20.e8. doi: 10.1016/j.annepidem.2020.08.006. Epub 2020 Sep 11.
4
-dependent coordination of mouse cardiac progenitor cell patterning and differentiation.依赖于协调的小鼠心脏祖细胞模式形成和分化。
Elife. 2020 Aug 17;9:e55124. doi: 10.7554/eLife.55124.
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Retinoic Acid Signaling and Heart Development.视黄酸信号传导与心脏发育
Subcell Biochem. 2020;95:119-149. doi: 10.1007/978-3-030-42282-0_5.
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Mechanisms of retinoic acid signaling during cardiogenesis.心脏发生过程中视黄酸信号传导的机制。
Mech Dev. 2017 Feb;143:9-19. doi: 10.1016/j.mod.2016.12.002. Epub 2016 Dec 19.
7
Birth defects in pregestational diabetes: Defect range, glycemic threshold and pathogenesis.孕前糖尿病中的出生缺陷：缺陷范围、血糖阈值及发病机制。
World J Diabetes. 2015 Apr 15;6(3):481-8. doi: 10.4239/wjd.v6.i3.481.
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Heart fields and cardiac morphogenesis.心脏区域与心脏形态发生
Cold Spring Harb Perspect Med. 2014 Oct 1;4(10):a015750. doi: 10.1101/cshperspect.a015750.