Welch Blair, Rose Rebecca, Myers Jessica, Drayton Jackson Meghan, Lien Izlin, Barbato Alana
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Riley Children's Health, Indiana University Health, Indianapolis, IN, USA.
J Perinatol. 2025 Jan;45(1):149-156. doi: 10.1038/s41372-024-02098-9. Epub 2024 Aug 28.
To decrease invasive mechanical ventilation exposure in the neonatal intensive care unit (NICU) in the first week of life for preterm infants with the global aim of decreasing bronchopulmonary dysplasia (BPD).
We created a quality improvement (QI) initiative to optimize early non-invasive respiratory support which launched in August 2021. Patients born at <32 weeks gestation and admitted to the NICU on non-invasive respiratory support were included.
Invasive mechanical ventilation exposure decreased from 38 to 25% with evidence of special cause variation beginning in August 2022. Infants born at ≥26 weeks were most impacted, with a 50% reduction, from 34 to 17%. While BPD rates decreased, there has not yet been evidence of special cause variation.
Invasive mechanical ventilation exposure for infants born at <32 weeks gestation decreased following the creation of a QI initiative focused on optimization and standardization of early non-invasive respiratory support.
降低新生儿重症监护病房（NICU）中出生后第一周的早产婴儿接受有创机械通气的比例，总体目标是减少支气管肺发育不良（BPD）。
我们开展了一项质量改进（QI）计划，以优化早期无创呼吸支持，该计划于2021年8月启动。纳入孕周<32周且因无创呼吸支持入住NICU的患者。
有创机械通气的比例从38%降至25%，从2022年8月开始有特殊原因变异的迹象。孕周≥26周的婴儿受影响最大，降低了50%，从34%降至17%。虽然BPD发生率有所下降，但尚无特殊原因变异的证据。
在开展一项专注于优化和标准化早期无创呼吸支持的QI计划后，孕周<32周婴儿的有创机械通气比例有所下降。
