血浆抗氧化能力与女性的饮食摄入、身体组成及生殖衰老阶段有关。

Plasma Antioxidant Capacity Is Related to Dietary Intake, Body Composition, and Stage of Reproductive Aging in Women.

作者信息

Tijerina Alexandra, Fonseca Diego, Aguilera-González Carlos J, Heya Michel Stéphane, Martínez Nancy, Sánchez Nydia, Bouzas Cristina, Tur Josep A, Salas Rogelio

机构信息

Faculty of Public Health and Nutrition, Autonomous University of Nuevo Leon, Monterrey 64460, Mexico.

Faculty of Biological Sciences, Autonomous University of Nuevo Leon, Monterrey 66455, Mexico.

出版信息

Antioxidants (Basel). 2024 Aug 2;13(8):940. doi: 10.3390/antiox13080940.

DOI:10.3390/antiox13080940

PMID:39199186

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11351479/

Abstract

BACKGROUND

women aging is a normal process of life; however, hormonal changes create an imbalance between prooxidants and antioxidants and could be measured as the antioxidant capability (AC) of an organism.

OBJECTIVE

to find the association between plasma AC levels, dietary intakes, and body composition in 18-64-year-old women living in the northeast of Mexico.

METHODS

A total of = 514 women (18-64 years old) were grouped according to STRAW criteria as reproductive, menopausal transition, and postmenopausal. Anthropometrics, body mass index (BMI), weight-hip ratio (WHR), and weight-height ratio WHtR were determined, and percentage of body fat was analyzed by bioelectrical impedance. Dietary intake of macronutrients and vitamins A, E, and C were analyzed by a 3-day food recall. The AC status in plasma was analyzed by the ORAC assay.

RESULTS

Plasma AC levels were higher in postmenopausal women (815 µmol TE/L), and menopausal transition women (806 µmol TE/L) than in reproductive women (633 µmol TE/L). BMI was overweight (>25 kg/m) in all three groups. WHtR and WHR are above the healthy limit of 0.5 and 0.8, respectively for both menopausal transition and postmenopausal women. In reproductive women, negative relationships were calculated between plasma AC and age ( = -0.250, = 0.007), BMI ( = -0.473, < 0.001), WHtR ( = -0.563, < 0.001), WHR ( = -0.499, < 0.001), and % body fat ( = -0.396, < 0.001). A negative association was determined between plasma AC and WHtR in reproductive women ( = -2.718, = 0.026). No association resulted for those in menopausal transition, and a positive association was obtained between plasma AC and protein ( = 0.001, = 0.024) and vitamin E ( = 0.003, = 0.013) intakes in postmenopausal women.

CONCLUSIONS

the antioxidant capability (AC) in plasma was lower in reproductive women, and anthropometric parameters marking decreased physical fitness were associated with decreased AC.

摘要

背景

女性衰老乃生命之正常过程；然而，激素变化会导致促氧化剂与抗氧化剂失衡，且可作为生物体的抗氧化能力（AC）进行测定。

目的

探寻墨西哥东北部18至64岁女性血浆AC水平、饮食摄入与身体组成之间的关联。

方法

总共514名（18至64岁）女性依据STRAW标准被分为生殖期、围绝经期过渡阶段和绝经后期。测定人体测量学指标、体重指数（BMI）、腰臀比（WHR）以及身高体重比（WHtR），并通过生物电阻抗分析身体脂肪百分比。通过3天饮食回顾法分析常量营养素以及维生素A、E和C的饮食摄入量。采用ORAC分析法分析血浆中的AC状态。

结果

绝经后期女性（815微摩尔TE/L）和围绝经期过渡阶段女性（806微摩尔TE/L）的血浆AC水平高于生殖期女性（633微摩尔TE/L）。所有三组的BMI均超重（>25千克/米²）。围绝经期过渡阶段女性和绝经后期女性的WHtR和WHR分别高于健康限值0.5和0.8。在生殖期女性中，血浆AC与年龄（r = -0.250，P = 0.007）、BMI（r = -0.473，P < 0.001）、WHtR（r = -0.563，P < 0.001）、WHR（r = -0.499，P < 0.001）以及体脂百分比（r = -0.396，P < 0.001）之间呈负相关。在生殖期女性中，血浆AC与WHtR之间呈负相关（r = -2.718，P = 0.026）。围绝经期过渡阶段女性未发现关联，绝经后期女性血浆AC与蛋白质摄入量（r = 0.001，P = 0.024）和维生素E摄入量（r = 0.003，P = 0.013）之间呈正相关。