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腘动脉腔内移植物感染的开放手术转换:病例报告与文献综述

Open Surgical Conversion of Popliteal Endograft Infection: Case Reports and Literature Review.

作者信息

Ascione Marta, Dajci Ada, Cangiano Rocco, Marzano Antonio, Molinari Andrea, Miceli Francesca, Di Girolamo Alessia, Leanza Cristiana, Oliva Alessandra, Di Marzo Luca, Mansour Wassim

机构信息

Vascular and Endovascular Surgery Division, Department of General Surgery and Surgical Specialties, Policlinico Umberto I, "Sapienza" University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

出版信息

Biomedicines. 2024 Aug 15;12(8):1855. doi: 10.3390/biomedicines12081855.

Abstract

BACKGROUND

Endovascular treatment of popliteal aneurysms (PA) has increased in the last few years, quickly becoming the main treatment performed in many vascular centers, based on the acceptable and promising outcomes reported in the literature. However, endograft infections after endovascular popliteal aneurysm repair (EPAR) are the most dangerous complications to occur as they involve serious local compromise and usually require open surgical conversion and device explantation to preserve the affected extremity.

CASE REPORT

We report two patients who were admitted to the emergency room of our hospital for pain and edema in the lower leg. Both patients had undergone exclusion of a ruptured PA a few years before by endovascular graft. CTA testing showed a significant volume of fluid-corpuscular collection related to perianeurysmal abscess collection in both cases. Blood cultures and drained material cultures were positive for in the first case and in the second. Prophylactic antibiotics were administered for 10 days, then patients underwent an open surgical conversion with the complete explantation of endovascular material and a femoro-popliteal bypass using an autologous vein in the first case and a biological bovine pericardium prosthesis in the second case. The infective department of our hospital had defined a discharged specific antibiotic therapy for each patient, based on intraoperative microbiological samples. Furthermore, we have examined the literature and found six more cases described in case report articles that refer to popliteal graft infections by different microorganisms, mostly presenting acute limb ischemia as the first symptom and suggesting endograft explantation with open conversion and autologous vein bypass as the commonest therapeutic choice.

CONCLUSIONS

The open surgical conversion of popliteal endograft infection is the best strategy to manage peripheral infection after an endovascular popliteal aneurysm repair procedure.

摘要

背景

在过去几年中,腘动脉瘤(PA)的血管内治疗有所增加,基于文献报道的可接受且有前景的结果,其迅速成为许多血管中心的主要治疗方法。然而,血管内腘动脉瘤修复术(EPAR)后的血管内移植物感染是最危险的并发症,因为它们会导致严重的局部损害,通常需要进行开放手术转换并取出移植物以保住患肢。

病例报告

我们报告了两名因小腿疼痛和水肿而入住我院急诊室的患者。两名患者均在数年前接受了血管内移植物治疗破裂的PA。CTA检查显示,两例均有大量与动脉瘤周围脓肿相关的液性细胞成分聚集。第一例血培养和引流物培养结果为[具体细菌名称1]阳性,第二例为[具体细菌名称2]阳性。预防性使用抗生素10天后,第一例患者接受了开放手术转换,完全取出血管内材料,并使用自体静脉进行了股腘动脉搭桥;第二例患者则使用生物牛心包假体进行了同样的手术。我院感染科根据术中微生物样本为每位患者确定了出院后的特定抗生素治疗方案。此外,我们查阅了文献,又发现了6例在病例报告文章中描述的腘动脉移植物感染病例,这些病例由不同微生物引起,大多以急性肢体缺血为首发症状,提示血管内移植物取出并进行开放转换及自体静脉搭桥是最常见的治疗选择。

结论

腘动脉血管内移植物感染的开放手术转换是处理血管内腘动脉瘤修复术后周围感染的最佳策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8090/11351597/7fe69f48959a/biomedicines-12-01855-g001a.jpg

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