Asiimwe Arnold Caleb, Marin Monica Pernia, Salvatore Mary
Department of Radiology, Columbia University Irving Medical Center, 177 Fort Washington Avenue, New York, NY 10032, USA.
Diagnostics (Basel). 2024 Aug 12;14(16):1748. doi: 10.3390/diagnostics14161748.
Breast density is an important marker for increased breast cancer risk, but the ideal marker would be more specific. Breast compactness, which reflects the focal density of collagen fibers, parallels breast cancer occurrence being highest in the upper outer quadrants of the breast. In addition, it peaks during the same time frame as breast cancer in women. Improved biomarkers for breast cancer risk could pave the way for patient-specific preventive strategies.
乳腺密度是乳腺癌风险增加的一个重要指标，但理想的指标应更具特异性。乳腺致密性反映了胶原纤维的局灶性密度，与乳腺癌的发生情况相似，在乳腺的上外象限最高。此外，它在女性乳腺癌发病的同一时间段达到峰值。改进的乳腺癌风险生物标志物可为针对患者的预防策略铺平道路。
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