Romano Lorenzo, Arcaniolo Davide, Spirito Lorenzo, Quattrone Carmelo, Bottone Francesco, Pandolfo Savio Domenico, Barone Biagio, Napolitano Luigi, Ditonno Francesco, Franco Antonio, Crocetto Felice, Romero-Otero Javier, Autorino Riccardo, De Sio Marco, Manfredi Celeste
Unit of Urology, Department of Woman Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Department of Urology, University of L'Aquila, 67010 L'Aquila, Italy.
Diagnostics (Basel). 2024 Aug 21;14(16):1819. doi: 10.3390/diagnostics14161819.
Premature ejaculation (PE) is a common male sexual dysfunction that can cause significant distress in the patient and partner. This study aimed to compare the current international guidelines on PE to highlight their similarities and differences. We examined the latest guidelines from the European Association of Urology (EAU), American Urological Association/Sexual Medicine Society of North America (AUA/SMSNA), and International Society of Sexual Medicine (ISSM) by comparing definitions, classifications, epidemiology, pathophysiology, and recommendations on diagnosis and therapy. The quality of guidelines was assessed using the Appraisal of Guidelines for Research and Evaluation (AGREE) Global Rating Scale (GRS). We found significant variations in the definitions of PE and recommendations on management of patients. The EAU guidelines were the most recent, the AUA/SMSNA guidelines lacked detail in some areas, and the ISSM guidelines were the most complete but also the least updated. The search for a unified definition and the development of standardized diagnostic and therapeutic pathways remain concrete issues to improve the management of patients with PE worldwide.
早泄（PE）是一种常见的男性性功能障碍，会给患者及其伴侣带来极大困扰。本研究旨在比较当前关于早泄的国际指南，以突出它们的异同。我们通过比较欧洲泌尿外科学会（EAU）、美国泌尿外科学会/北美性医学学会（AUA/SMSNA）和国际性医学学会（ISSM）的最新指南中关于早泄的定义、分类、流行病学、病理生理学以及诊断和治疗的建议来进行研究。使用指南研究与评价的评估（AGREE）全球评级量表（GRS）对指南质量进行评估。我们发现早泄的定义以及患者管理建议存在显著差异。EAU指南是最新的，AUA/SMSNA指南在某些领域缺乏细节，而ISSM指南是最完整的，但也是更新最少的。寻求统一的定义以及制定标准化的诊断和治疗途径仍然是改善全球早泄患者管理的具体问题。
