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妊娠期间与镁和维生素 D 营养素相关的心血代谢危险因素:叙述性综述。

Cardiometabolic Risk Factors Associated with Magnesium and Vitamin D Nutrients during Pregnancy-A Narrative Review.

机构信息

Department of Public Health, College of Health, Community, and Policy, University of Texas at San Antonio, San Antonio, TX 78249, USA.

Foundation for Maternal, Infant, and Lactation Knowledge, San Antonio, TX 78249, USA.

出版信息

Nutrients. 2024 Aug 9;16(16):2630. doi: 10.3390/nu16162630.

DOI:10.3390/nu16162630
PMID:39203767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11357465/
Abstract

This narrative review comprehensively explores the cardiometabolic implications of two vital nutrients, magnesium and vitamin D, during gestation. Magnesium, a key regulator of vascular tone, glucose metabolism, and insulin sensitivity, plays a crucial role in mitigating gestational hypertension and diabetes, a point this review underscores. Conversely, vitamin D, critical for immune response and calcium level maintenance, is linked to gestational diabetes and hypertensive disorders of pregnancy. The authors aim to enhance comprehension of the complex interaction between these nutrients and cardiometabolic function in pregnancy, knowledge that is pivotal for optimizing maternal-fetal outcomes. The mother's health during pregnancy significantly influences the long-term development of the fetus. Recognizing the impact of these nutrient deficiencies on the physiology of cardiometabolic cycles underscores the importance of adequate nutritional support during pregnancy. It also emphasizes the pressing need for future research and targeted interventions to alleviate the burden of pregnancy complications, highlighting the crucial role of healthcare professionals, researchers, and policy makers in obstetrics and gynecology in this endeavor.

摘要

这篇叙述性评论全面探讨了镁和维生素 D 这两种重要营养物质在妊娠期间对心血管代谢的影响。镁是血管张力、葡萄糖代谢和胰岛素敏感性的关键调节剂,在减轻妊娠高血压和糖尿病方面起着至关重要的作用,这也是本综述强调的一点。相比之下,维生素 D 对于免疫反应和钙水平的维持至关重要,与妊娠糖尿病和妊娠高血压疾病有关。作者旨在提高对这些营养物质与妊娠期间心血管代谢功能之间复杂相互作用的理解,这对于优化母婴结局至关重要。母亲在怀孕期间的健康状况会显著影响胎儿的长期发育。认识到这些营养缺乏对心血管代谢循环生理的影响,凸显了在怀孕期间提供充足营养支持的重要性。它还强调了未来研究和有针对性干预措施的迫切需要,以减轻妊娠并发症的负担,突显了妇产科领域的医疗保健专业人员、研究人员和政策制定者在这方面的重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0e/11357465/87f5f5cac2fa/nutrients-16-02630-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0e/11357465/c0a09f088cbf/nutrients-16-02630-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0e/11357465/87f5f5cac2fa/nutrients-16-02630-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0e/11357465/c0a09f088cbf/nutrients-16-02630-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0e/11357465/87f5f5cac2fa/nutrients-16-02630-g002.jpg

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本文引用的文献

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J Health Popul Nutr. 2023 Jul 27;42(1):74. doi: 10.1186/s41043-023-00423-0.
2
Magnesium Deficiency and Cardiometabolic Disease.镁缺乏与心脏代谢疾病。
Nutrients. 2023 May 17;15(10):2355. doi: 10.3390/nu15102355.
3
Association of dietary calcium with mortality from all causes, cardiovascular disease and cancer in people with hypertension.高血压人群的膳食钙与全因死亡率、心血管疾病和癌症的关系。
J Clin Hypertens (Greenwich). 2023 May;25(5):480-488. doi: 10.1111/jch.14657. Epub 2023 Apr 13.
4
Inappropriate supplementation of Vitamin D can result in toxicity: a crosssectional study of paediatrics population.维生素D补充不当可导致中毒:一项针对儿科人群的横断面研究。
J Pak Med Assoc. 2023 Mar;73(3):500-504. doi: 10.47391/JPMA.5512.
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The Association Between Serum Magnesium Levels and Gestational Diabetes Mellitus: a Systematic Review and Meta-Analysis.血清镁水平与妊娠期糖尿病的关系:系统评价和荟萃分析。
Biol Trace Elem Res. 2023 Nov;201(11):5115-5125. doi: 10.1007/s12011-023-03591-6. Epub 2023 Feb 15.
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