Department of Internal Medicine, College of Korean Medicine, Semyung University, Semyeong-ro 65, Jecheon-si 27136, Republic of Korea.
RnBS Corporation, Seoul 06032, Republic of Korea.
Nutrients. 2024 Aug 13;16(16):2670. doi: 10.3390/nu16162670.
This randomised double-blind placebo-controlled trial evaluated the efficacy and safety of fermented gold kiwi (FGK) in improving gastrointestinal health. A total of 100 participants were enrolled and randomly assigned to treatment or placebo groups. Over 8 weeks, the participants consumed an FGK or placebo preparation daily. Primary outcomes included changes in gastrointestinal symptoms assessed using the Gastrointestinal Symptom Rating Scale (GSRS) and the Korean version of the Nepean Dyspepsia Index (NDI-K), as well as quality of life assessed using the Functional Dyspepsia-related Quality of Life questionnaire. The FGK group showed significant improvements in GSRS and NDI-K total and subdomain scores compared with the placebo group. Moreover, the quality of life scores were significantly better in the FGK group than in the placebo group. Safety evaluations revealed no significant adverse events or clinically meaningful changes upon assessing laboratory test results. This study demonstrated that FGK is a safe and effective dietary supplement for improving gastrointestinal health in adults with gastrointestinal symptoms.
这项随机双盲安慰剂对照试验评估了发酵金奇异果（FGK）改善胃肠道健康的功效和安全性。共有 100 名参与者入组，并随机分配到治疗组或安慰剂组。在 8 周的时间里，参与者每天服用 FGK 或安慰剂制剂。主要结局包括使用胃肠道症状评分量表（GSRS）和韩国版消化不良指数（NDI-K）评估的胃肠道症状变化，以及使用功能性消化不良相关生活质量问卷评估的生活质量。与安慰剂组相比，FGK 组的 GSRS 和 NDI-K 总分和各分项评分均有显著改善。此外，FGK 组的生活质量评分明显优于安慰剂组。安全性评估显示，在评估实验室检测结果时，未发现明显的不良事件或有临床意义的变化。这项研究表明，FGK 是一种安全有效的膳食补充剂，可改善有胃肠道症状的成年人的胃肠道健康。
