Department of Pharmacy, School of Health Sciences, Frederick University, Nicosia 1036, Cyprus.
Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotelian University of Thessaloniki, 54124 Thessaloniki, Greece.
Nutrients. 2024 Aug 16;16(16):2740. doi: 10.3390/nu16162740.
Vitamins are micronutrients necessary for the normal function of the body. Although each vitamin has different physicochemical properties and a specific role in maintaining life, they may also possess a common characteristic, i.e., antioxidant activity. Oxidative stress can harm all the main biological structures leading to protein, DNA and lipid oxidation, with concomitant impairment of the cell. It has been established that oxidative stress is implicated in several pathological conditions such as atherosclerosis, diabetes, obesity, inflammation and metabolic syndrome. In this review we investigate the influence of oxidative stress on the above conditions, examine the interrelation between oxidative stress and inflammation and point out the importance of vitamins in these processes, especially in oxidative load manipulation and metabolic abnormalities.
维生素是维持身体正常功能所必需的微量营养素。虽然每种维生素都具有不同的理化性质和在维持生命方面的特定作用，但它们也可能具有共同的特征，即抗氧化活性。氧化应激会损害所有主要的生物结构，导致蛋白质、DNA 和脂质氧化，同时损害细胞。已经确定氧化应激与几种病理状况有关，如动脉粥样硬化、糖尿病、肥胖、炎症和代谢综合征。在这篇综述中，我们研究了氧化应激对上述情况的影响，检查了氧化应激与炎症之间的相互关系，并指出了维生素在这些过程中的重要性，特别是在氧化负荷的操纵和代谢异常方面。
