Ke Mengyuan, Kumar Abhishek, Ansbæk Thor E, Leitgeb Rainer A
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090 Wien, Austria.
Wavesense Engineering GmbH, 1190 Wien, Austria.
Sensors (Basel). 2024 Aug 10;24(16):5161. doi: 10.3390/s24165161.
Ocular aberrometry with a wide dynamic range for assessing vision performance and anterior segment imaging that provides anatomical details of the eye are both essential for vision research and clinical applications. Defocus error is a major limitation of digital wavefront aberrometry (DWA), as the blurring of the detected point spread function (PSF) significantly reduces the signal-to-noise ratio (SNR) beyond the ±3 D range. With the aid of Badal-like precompensation of defocus, the dynamic defocus range of the captured aberrated PSFs can be effectively extended. We demonstrate a dual-modality MHz VCSEL-based swept-source OCT (SS-OCT) system with easy switching between DWA and OCT imaging modes. The system is capable of measuring aberrations with defocus dynamic range of 20 D as well as providing fast anatomical imaging of the anterior segment at an A-scan rate of 1.6 MHz.
具有宽动态范围以评估视觉性能的眼像差测量以及提供眼睛解剖细节的前段成像，对于视觉研究和临床应用都至关重要。散焦误差是数字波前像差测量（DWA）的一个主要限制，因为检测到的点扩散函数（PSF）的模糊会显著降低超过±3 D范围的信噪比（SNR）。借助类似巴达尔的散焦预补偿，可以有效扩展捕获的像差PSF的动态散焦范围。我们展示了一种基于MHz垂直腔面发射激光器（VCSEL）的双模态扫频源光学相干断层扫描（SS-OCT）系统，该系统能够在DWA和OCT成像模式之间轻松切换。该系统能够测量散焦动态范围为20 D的像差，并以1.6 MHz的A扫描速率提供前段的快速解剖成像。
