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年龄相关性黄斑变性中的脉络膜毛细血管。

Choriocapillaris in Age-Related Macular Degeneration.

机构信息

University of Turin, Department of Surgical Sciences, Turin, Italy.

University of Bari "Aldo Moro", Department of Translational Biomedicine Neuroscience, Bari, Italy.

出版信息

Turk J Ophthalmol. 2024 Aug 28;54(4):228-234. doi: 10.4274/tjo.galenos.2024.04608.

DOI:10.4274/tjo.galenos.2024.04608
PMID:39205438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11590706/
Abstract

Age-related macular degeneration (AMD) is a multifactorial disease characterized by progressive alterations of different retinal structures ultimately leading to vision loss. Among these, the choriocapillaris (CC) has been found to be affected in different stages of AMD. In this review we provide a discussion on the different stages of AMD, focusing particularly on the alterations involving the CC. This has been possible thanks to the introduction of optical coherence tomography-angiography, a recently developed imaging technique which allows the detection of blood flow in choroidal vessels. Therefore, the aim of this review is to provide a description of the various alterations involving the CC in the different stages of AMD.

摘要

年龄相关性黄斑变性(AMD)是一种多因素疾病,其特征是不同视网膜结构的进行性改变,最终导致视力丧失。在这些改变中,脉络膜毛细血管(CC)已被发现存在于 AMD 的不同阶段。在这篇综述中,我们讨论了 AMD 的不同阶段,特别关注涉及 CC 的改变。这要归功于光学相干断层扫描血管造影术的引入,这是一种最近开发的成像技术,可以检测脉络膜血管中的血流。因此,本综述的目的是描述 AMD 不同阶段中涉及 CC 的各种改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b888/11590706/6fae80ae93bc/TurkJOphthalmol-54-228-figure-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b888/11590706/91941f21f0fd/TurkJOphthalmol-54-228-figure-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b888/11590706/a54eb2042b39/TurkJOphthalmol-54-228-figure-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b888/11590706/6fae80ae93bc/TurkJOphthalmol-54-228-figure-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b888/11590706/91941f21f0fd/TurkJOphthalmol-54-228-figure-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b888/11590706/a54eb2042b39/TurkJOphthalmol-54-228-figure-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b888/11590706/6fae80ae93bc/TurkJOphthalmol-54-228-figure-3.jpg

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本文引用的文献

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Age-Related Macular Degeneration: A Review.年龄相关性黄斑变性:综述。
JAMA. 2024 Jan 9;331(2):147-157. doi: 10.1001/jama.2023.26074.
2
The Impact of Diabetic Retinopathy on the Choriocapillaris in Neovascular AMD.糖尿病性视网膜病变对新生血管性年龄相关性黄斑变性脉络膜毛细血管的影响。
Invest Ophthalmol Vis Sci. 2023 Nov 1;64(14):32. doi: 10.1167/iovs.64.14.32.
3
Pushing Retinal Imaging Forward: Innovations and Their Clinical Meaning - The 2022 Ophthalmologica Lecture.推动视网膜成像向前发展:创新及其临床意义——2022年眼科学讲座
Ophthalmologica. 2023;246(5-6):278-294. doi: 10.1159/000533910. Epub 2023 Sep 13.
4
Clinicopathologic Findings in Three Siblings With Geographic Atrophy.三位同胞兄妹的临床病理发现:地图状萎缩。
Invest Ophthalmol Vis Sci. 2023 Mar 1;64(3):2. doi: 10.1167/iovs.64.3.2.
5
Topographical Analysis of the Choriocapillaris Reperfusion After Loading Anti-VEGF Therapy in Neovascular AMD.抗血管内皮生长因子治疗后新生血管性年龄相关性黄斑变性脉络膜毛细血管再灌注的地形分析。
Transl Vis Sci Technol. 2022 Sep 1;11(9):18. doi: 10.1167/tvst.11.9.18.
6
Choriocapillaris: Fundamentals and advancements.脉络膜毛细血管:基础与进展。
Prog Retin Eye Res. 2022 Mar;87:100997. doi: 10.1016/j.preteyeres.2021.100997. Epub 2021 Jul 19.
7
Age-Related Macular Degeneration: Pathophysiology, Management, and Future Perspectives.年龄相关性黄斑变性:病理生理学、管理及未来展望
Ophthalmologica. 2021;244(6):495-511. doi: 10.1159/000517520. Epub 2021 Jun 15.
8
Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).扫频源光学相干断层扫描(OCT)和光相干断层扫描血管造影(OCTA)在视网膜中的应用。
Prog Retin Eye Res. 2021 Sep;84:100951. doi: 10.1016/j.preteyeres.2021.100951. Epub 2021 Jan 28.
9
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Retina. 2021 Sep 1;41(9):1819-1827. doi: 10.1097/IAE.0000000000003119.
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Correlations Between Choriocapillaris and Choroidal Measurements and the Growth of Geographic Atrophy Using Swept Source OCT Imaging.使用扫频源光学相干断层扫描成像技术测量脉络膜毛细血管和脉络膜与地图样萎缩进展之间的相关性
Am J Ophthalmol. 2021 Apr;224:321-331. doi: 10.1016/j.ajo.2020.12.015. Epub 2020 Dec 24.