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表面改性V级钛合金的生物学和物理学特性

Biological and Physical Characterization of Surface-Modified Grade V Titanium Alloy.

作者信息

Kakunje Mahesh, Nambiar Supriya, Isloor Arun M, Kabekkodu Shamaprasada, Bhat Udaya

机构信息

Department of Orthodontics and Dentofacial Orthopedics Manipal College of Dental Sciences Mangalore Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.

Membrane and Separation Technology Laboratory Department of Chemistry National Institute of Technology Karnataka, Surathkal, Mangalore 575 025, India.

出版信息

Int J Dent. 2024 Aug 21;2024:6662866. doi: 10.1155/2024/6662866. eCollection 2024.

DOI:10.1155/2024/6662866
PMID:39206223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11357819/
Abstract

Surface modification and biomimetic approaches have been widely used to enhance bioinert substances. It is not very clear whether surface alterations and polymer coatings on titanium make it more biologically active and enhance cell adhesion. We tried to focus on the physical and biological characterization of surface-modified titanium disks. Four different surface modifications were done for the titanium disks, ranging from acid etching, sandblasting, polydopamine coating, and polydopamine-based chitosan coating, and were compared with disks without any surface modification. The disks were studied for physical characteristics like surface roughness and contact angle. Human gingival fibroblasts were used to investigate the biological effects of surface modification of titanium alloy surfaces. The wettability of chitosan-coated, acid-etched, and polydopamine-coated titanium was much better than that of the sandblasted surface, indicating that surface energy was higher for acid-etched and coated surfaces than others. The cell seeding with fibroblasts showed increased adhesion to the smoother surfaces as compared to the rougher surfaces. Polydopamine coatings on titanium disks showed the most favorable physical and biological properties compared to others and can be a good surface coating for in vivo implants.

摘要

表面改性和仿生方法已被广泛用于增强生物惰性物质。钛表面的改变和聚合物涂层是否使其更具生物活性并增强细胞粘附尚不清楚。我们试图专注于表面改性钛盘的物理和生物学特性。对钛盘进行了四种不同的表面改性，包括酸蚀、喷砂、聚多巴胺涂层和基于聚多巴胺的壳聚糖涂层，并与未进行任何表面改性的盘进行比较。研究了这些盘的表面粗糙度和接触角等物理特性。使用人牙龈成纤维细胞来研究钛合金表面改性的生物学效应。壳聚糖涂层、酸蚀和聚多巴胺涂层钛的润湿性比喷砂表面好得多，表明酸蚀和涂层表面的表面能高于其他表面。与较粗糙表面相比，成纤维细胞接种显示出对较光滑表面的粘附增加。与其他涂层相比，钛盘上的聚多巴胺涂层显示出最有利的物理和生物学特性，并且可以成为体内植入物的良好表面涂层。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/ef0bb81b06a8/IJD2024-6662866.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/16bd675a1c22/IJD2024-6662866.001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/c0e6f92f7332/IJD2024-6662866.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/029e922431cb/IJD2024-6662866.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/ef0bb81b06a8/IJD2024-6662866.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/16bd675a1c22/IJD2024-6662866.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/56a0d3b5a6c0/IJD2024-6662866.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/7c126611e980/IJD2024-6662866.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/a557333324c6/IJD2024-6662866.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/5886ead91258/IJD2024-6662866.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/e5b50322533a/IJD2024-6662866.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/c0e6f92f7332/IJD2024-6662866.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/029e922431cb/IJD2024-6662866.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95f/11357819/ef0bb81b06a8/IJD2024-6662866.009.jpg

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本文引用的文献

1
Recent advances in the medical applications of hemostatic materials.止血材料在医学应用中的最新进展。
Theranostics. 2023 Jan 1;13(1):161-196. doi: 10.7150/thno.79639. eCollection 2023.
2
Titanium Dental Implants: An Overview of Applied Nanobiotechnology to Improve Biocompatibility and Prevent Infections.钛牙种植体：应用纳米生物技术改善生物相容性和预防感染的概述
Materials (Basel). 2022 Apr 27;15(9):3150. doi: 10.3390/ma15093150.
3
Chitosan: A Natural Biopolymer with a Wide and Varied Range of Applications.壳聚糖：一种具有广泛多样应用的天然生物聚合物。
Molecules. 2020 Sep 1;25(17):3981. doi: 10.3390/molecules25173981.
4
From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material.从仿生胶水到医学：聚多巴胺作为一种生物医学材料。
Materials (Basel). 2020 Apr 7;13(7):1730. doi: 10.3390/ma13071730.
5
Attachment and Growth of Periodontal Cells on Smooth and Rough Titanium.牙周细胞在光滑和粗糙钛表面的附着与生长
Int J Oral Maxillofac Implants. 1994 May/Jun;9(3):289-297.
6
Polydopamine-Assisted Surface Modification for Bone Biosubstitutes.用于骨生物替代物的聚多巴胺辅助表面修饰
Biomed Res Int. 2016;2016:2389895. doi: 10.1155/2016/2389895. Epub 2016 Aug 9.
7
Surface functionalization of titanium with hyaluronic acid/chitosan polyelectrolyte multilayers and RGD for promoting osteoblast functions and inhibiting bacterial adhesion.用透明质酸/壳聚糖聚电解质多层膜和RGD对钛进行表面功能化以促进成骨细胞功能并抑制细菌黏附。
Biomaterials. 2008 Apr;29(10):1412-21. doi: 10.1016/j.biomaterials.2007.12.019. Epub 2008 Jan 10.
8
XPS study on the use of 3-aminopropyltriethoxysilane to bond chitosan to a titanium surface.关于使用3-氨丙基三乙氧基硅烷将壳聚糖与钛表面结合的X射线光电子能谱研究。
Langmuir. 2007 Jun 5;23(12):6645-51. doi: 10.1021/la063284v. Epub 2007 May 9.
9
Systematic study of osteoblast and fibroblast response to roughness by means of surface-morphology gradients.通过表面形态梯度对成骨细胞和成纤维细胞对粗糙度的反应进行系统研究。
Biomaterials. 2007 Apr;28(13):2175-82. doi: 10.1016/j.biomaterials.2007.01.019. Epub 2007 Jan 14.
10
Effect of surface processing on the attachment, orientation, and proliferation of human gingival fibroblasts on titanium.表面处理对人牙龈成纤维细胞在钛表面的附着、取向和增殖的影响。
J Biomed Mater Res. 1992 Oct;26(10):1325-41. doi: 10.1002/jbm.820261006.