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SARS-CoV-2感染患者溃疡性病变的低强度激光治疗

Treatment of Ulcerative Lesions with Low-level Laser Therapy in a Patient with SARS-CoV-2.

作者信息

Castro Evllen do Vale, Freitas Joao Victor de Paula, Oliveira Francisco Artur Forte, Maia Lucas Alexandre, Dantas Thinali Sousa, Forte Clarissa Pessoa Fernandes

机构信息

Christus University Center, Fortaleza, Brazil.

Department of Dentistry, Christus University Center, Fortaleza, Brazil.

出版信息

Contemp Clin Dent. 2024 Apr-Jun;15(2):138-142. doi: 10.4103/ccd.ccd_399_23. Epub 2024 Jul 10.

Abstract

Ulcerated lesions have been observed in SARS-CoV-2 patients and their treatment is a challenge. We aim to report the treatment of oral lesions with low-level laser therapy (LLLT) in a patient with SARS-CoV-2. The patient diagnosed with COVID-19 was admitted to the intensive care unit, on mechanical ventilation, and on a nasogastric tube diet that persisted due to oral lesions. Painful ulcerated lesions, clinically diagnosed as viral ulcer, were found on the tongue, palate, labial commissure, and oropharynx during the oral evaluation. An antimicrobial photodynamic therapy with methylene blue and red laser (high energy) was performed, followed by treatment with LLLT with red laser. Significant clinical improvement of the lesions was observed after seven sessions of LLLT, with the oral diet being reestablished. Oral mucosal lesions in patients with COVID-19 are usually symptomatic and with onset after systemic symptoms. LLLT has been used in the management of these lesions, with promising results.

摘要

在新型冠状病毒肺炎(SARS-CoV-2)患者中观察到了溃疡性病变,其治疗是一项挑战。我们旨在报告低强度激光疗法(LLLT)对一名SARS-CoV-2患者口腔病变的治疗情况。该确诊为新型冠状病毒病(COVID-19)的患者被收入重症监护病房,接受机械通气,并因口腔病变持续接受鼻饲饮食。口腔检查时,在舌、腭、唇联合处和口咽发现了临床上诊断为病毒性溃疡的疼痛性溃疡性病变。先进行了亚甲蓝和红色激光(高能)的抗菌光动力疗法,随后用红色激光进行LLLT治疗。经过七次LLLT治疗后,病变有显著临床改善,恢复了经口饮食。COVID-19患者的口腔黏膜病变通常有症状,且在全身症状出现后发作。LLLT已用于这些病变的管理,效果 promising 。 (注:原文中“promising”直译为“有希望的”,结合语境这里可理解为“效果良好”等类似意思,因要求不添加解释,所以保留英文)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/11349074/ef19a9d54004/CCD-15-138-g001.jpg

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