Shibl A M
Rev Infect Dis. 1985 Jan-Feb;7(1):51-65. doi: 10.1093/clinids/7.1.51.
Microbial adherence to epithelial cell surfaces has been implicated as the first step in the initiation of several infectious diseases. Subinhibitory concentrations of antibiotics affect the adherence properties of microorganisms in various ways. They can inhibit the expression of fimbriae and the synthesis of other surface components, and they may also cause the release of constituents from the cell. The ability of antibiotics to affect the properties of microbial adherence to cell surfaces may be an important criterion in selecting an antibiotic for therapy.
微生物黏附于上皮细胞表面被认为是多种传染病发病的第一步。亚抑菌浓度的抗生素以多种方式影响微生物的黏附特性。它们可以抑制菌毛的表达和其他表面成分的合成，还可能导致细胞成分的释放。抗生素影响微生物黏附细胞表面特性的能力可能是选择治疗用抗生素的一个重要标准。
