Department of Artificial Intelligence and Machine Learning, School of Engineering, Malla Reddy University, Hyderabad, India.
Department of Computer Science and Engineering, AVN Institute of Engineering and Technology, Hyderabad, India.
Int Ophthalmol. 2024 Aug 29;44(1):359. doi: 10.1007/s10792-024-03279-3.
The state of the human eye's blood vessels is a crucial aspect in the diagnosis of ophthalmological illnesses. For many computer-aided diagnostic systems, precise retinal vessel segmentation is an essential job. However, it remains a difficult task due to the intricate vascular system of the eye. Although many different vascular segmentation techniques have already been presented, additional study is still required to address the problem of inadequate segmentation of thin and tiny vessels.
In this work, we introduce the Spatial Attention U-Net (SAU-Net) model with harris hawks' optimization (HHO), a lightweight network that can be applied as a data augmentation technique to improve the efficiency of the existing annotated samples without the need of thousands of training instances for Retinal Blood Vessel and Optic Disc Segmentation. The SAU-Net-HHO implementation uses a spatially inferred attention map multiplied by the input feature map for adaptive feature enhancement. U-Net convolutional blocks have been replaced with structured dropout blocks in the proposed network to prevent overfitting. Data from both vascular extraction (DRIVE) and structured analysis of the retina (STARE) are used to evaluate SAU-Net-HHO performance.
The results show that the proposed SAU-Net-HHO performs well on both datasets. Analysing the obtained results, an average of 98.5% accuracy and Specificity 96.7% was achieved for DRIVE dataset and 97.8% accuracy and specificity 94.5% for STARE dataset. The proposed method yields numerical results with average values that are on par with those of state-of-the-art methods.
Visual inspection has revealed that the suggested method can segment thin and tiny vessels with greater accuracy than previous methods. It also demonstrates its potential for real-life clinical application.
人眼血管的状态是眼科疾病诊断的关键方面。对于许多计算机辅助诊断系统,精确的视网膜血管分割是一项必不可少的工作。然而,由于眼睛的血管系统错综复杂,这仍然是一项艰巨的任务。尽管已经提出了许多不同的血管分割技术,但仍需要进一步研究来解决细小血管分割不足的问题。
在这项工作中,我们引入了带有哈里斯鹰优化(HHO)的空间注意 U-Net(SAU-Net)模型,这是一个轻量级网络,可以作为数据增强技术应用,在不需要数千个视网膜血管和视盘分割的标注样本的情况下,提高现有样本的效率。SAU-Net-HHO 实现使用空间推断的注意力图乘以输入特征图进行自适应特征增强。在提出的网络中,用结构化的丢弃块替换 U-Net 卷积块,以防止过拟合。从血管提取(DRIVE)和视网膜结构分析(STARE)两个数据集评估 SAU-Net-HHO 的性能。
结果表明,所提出的 SAU-Net-HHO 在两个数据集上都表现良好。通过对获得的结果进行分析,在 DRIVE 数据集上,平均准确率和特异性分别达到 98.5%和 96.7%,在 STARE 数据集上,平均准确率和特异性分别达到 97.8%和 94.5%。所提出的方法产生的数值结果平均值与最先进的方法相当。
通过视觉检查发现,该方法可以比以前的方法更准确地分割细小血管,并且具有潜在的实际临床应用价值。