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成人先天性肺畸形。

Congenital Lung Anomalies in Adults.

机构信息

From San Lucas Diagnóstico, 25 de Mayo 1941, 3300, Posadas, Argentina (M.M.N.); Department of Radiology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina (G.D.); Department of Radiology, University of Texas Health Science Center, San Antonio, TX (C.S.R.); Departments of Radiology (R.K., N.R., D.V.) and Pathology (N.S.), University of Colorado Anschutz Medical Campus, Aurora, CO; and Department of Radiology, Hospital San Juan de Dios, HT Médica, Córdoba, Spain (J.B.).

出版信息

Radiographics. 2024 Sep;44(9):e240017. doi: 10.1148/rg.240017.

Abstract

Congenital lung anomaly (CLA) refers to a rare group of malformations that are typically identified prenatally or in early childhood. However, a significant proportion of cases evade detection until adulthood and either are incidentally discovered or manifest with symptoms of recurrent respiratory infection or pulmonary hemorrhage. While most CLAs have characteristic imaging findings at CT and MRI, they remain a diagnostic challenge due to the infrequency with which they are encountered in adults. Radiologists frequently play a pivotal role in suggesting the diagnosis and guiding appropriate management strategies, and recognition of characteristic imaging patterns is crucial for accurate diagnosis. The authors examine the imaging appearances and clinical manifestations in adult patients with CLA, with a focus on patients who have bronchopulmonary involvement and those with combined bronchopulmonary and vascular anomalies. Entities discussed include bronchogenic cyst, bronchial atresia, congenital lobar overinflation, congenital pulmonary airway malformation, proximal interruption of the pulmonary artery, bronchopulmonary sequestration, hypogenetic lung syndrome, placental transmogrification of the lung, and hybrid lesions. Common complications that may arise in these patients are discussed and illustrated. RSNA, 2024

摘要

先天性肺异常(CLA)是一组罕见的畸形,通常在产前或儿童早期被发现。然而,相当一部分病例直到成年后才被发现,要么是偶然发现的,要么表现为反复呼吸道感染或肺出血的症状。虽然大多数 CLA 在 CT 和 MRI 上具有特征性的影像学表现,但由于成人中罕见,因此仍然是一个诊断挑战。放射科医生经常在提示诊断和指导适当的管理策略方面发挥关键作用,识别特征性的影像学模式对于准确诊断至关重要。作者检查了成年 CLA 患者的影像学表现和临床表现,重点关注有支气管肺受累和同时有支气管肺和血管异常的患者。讨论的实体包括支气管囊肿、支气管闭锁、先天性肺过度充气、先天性肺气道畸形、肺动脉近端中断、支气管肺隔离症、肺发育不全综合征、胎盘肺转位和混合性病变。讨论并说明了这些患者可能出现的常见并发症。RSNA,2024

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