School of Food Science and Technology, Shihezi University, Shihezi, Xinjiang 832003, China; Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials & Devices, Guangzhou Key Laboratory of Sensing Materials & Devices, Center for Advanced Analytical Science, School of Chemistry and Chemical Engineering, School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou 510006, China; Key Laboratory of Agricultural Product Processing and Quality Control of Specialty (Co-construction by Ministry and Province), Shihezi, Xinjiang 832003, China; Key Laboratory for Food Nutrition and Safety Control of Xinjiang Production and Construction Corps, Shihezi University, Shihezi, Xinjiang 832003, China.
Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials & Devices, Guangzhou Key Laboratory of Sensing Materials & Devices, Center for Advanced Analytical Science, School of Chemistry and Chemical Engineering, School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou 510006, China.
Food Chem. 2025 Jan 1;462:140939. doi: 10.1016/j.foodchem.2024.140939. Epub 2024 Aug 28.
Phoxim, extensively utilized in agriculture as an organothiophosphate insecticide, has the potential to cause neurotoxicity and pose human health hazards. In this study, an electrochemical enzyme biosensor based on TiC MXene/MoS@AuNPs/AChE was constructed for the sensitive detection of phoxim. The two-dimensional multilayer structure of TiC MXene provides a robust framework for MoS, leading to an expansion of the specific surface area and effectively preventing re-stacking of TiC MXene. Additionally, the synergistic effect of self-reduced grown AuNPs with MoS further improves the electrical conductivity of the composites, while the robust framework provides a favorable microenvironment for immobilization of enzyme molecules. TiC MXene/MoS@AuNPs electrochemical enzyme sensor showed a significant response to phoxim in the range of 1 × 10 M to 1 × 10 M with a detection limit of 5.29 × 10 M. Moreover, the sensor demonstrated excellent repeatability, reproducibility, and stability, thereby showing its promising potential for real sample detection.
辛硫磷作为一种有机磷杀虫剂，在农业中广泛应用，但具有潜在的神经毒性和对人类健康的危害。本研究构建了一种基于 TiC MXene/MoS@AuNPs/AChE 的电化学酶生物传感器，用于灵敏检测辛硫磷。TiC MXene 的二维多层结构为 MoS 提供了一个坚固的骨架，从而扩展了比表面积，并有效防止 TiC MXene 的重新堆积。此外，自还原生长的 AuNPs 与 MoS 的协同作用进一步提高了复合材料的电导率，而坚固的骨架为酶分子的固定提供了有利的微环境。TiC MXene/MoS@AuNPs 电化学酶传感器对辛硫磷的响应范围为 1×10^-7 M 至 1×10^-5 M，检测限为 5.29×10^-7 M。此外，该传感器表现出优异的重复性、重现性和稳定性，因此显示出其在实际样品检测中的应用潜力。
