Key Laboratory of Applied Chemistry, Department of Applied Chemistry, Yanshan University, Qinhuangdao 066004, PR China.
Key Laboratory of Applied Chemistry, Department of Applied Chemistry, Yanshan University, Qinhuangdao 066004, PR China.
J Hazard Mater. 2019 Jul 5;373:367-376. doi: 10.1016/j.jhazmat.2019.03.083. Epub 2019 Mar 23.
Transition metal oxides (TMOs) derived from metal - organic frameworks (MOF) combined with two-dimensional (2D) transition metal carbides possibly pave an innovative pathway for designing promising biosensors. Herein, a novel electrochemical sensing platform has been fabricated for ultra-sensitive determination of organophosphorus pesticides (OPs), based on MOF-derived MnO/MnO and TiC MXene/Au NPs composites. Remarkably, the three-dimensional (3D) MnO/MnO hierarchical microcuboids derived from Mn-MOF are composed of vertically aligned, highly ordered nanosheets, and further combined with MXene/Au NPs yields synergistic signal amplification effect, with outstanding electrochemical performance, large specific surface area, and good environmental biocompatibility. Under the optimum conditions, the reported sensing platform AChE-Chit/MXene/Au NPs/MnO/MnO/GCE can be utilized to detect methamidophos in a broad concentration range (10-10 M), together with a good linearity (R = 0.995). Besides that, the biosensor possesses a low limit of detection (1.34 × 10 M), which far exceeds the maximum residue limits (MRLs) for methamidophos (0.01 mg/kg) established by European Union. Additionally, the feasibility of the proposed biosensor for detecting methamidophos in real samples has been demonstrated with excellent recoveries (95.2%-101.3%). Interestingly, the unique structures and remarkable properties of these composites make them attractive materials for various electrochemical sensors for monitoring either pesticide residuals or other environmentally deleterious chemicals.
过渡金属氧化物（TMOs）衍生自金属有机骨架（MOF）与二维（2D）过渡金属碳化物的结合，可能为设计有前途的生物传感器开辟一条创新途径。在此，基于 MOF 衍生的 MnO/MnO 和 TiC MXene/Au NPs 复合材料，构建了一种新颖的电化学传感平台，用于超灵敏地测定有机磷农药（OPs）。值得注意的是，由 Mn-MOF 衍生的三维（3D）MnO/MnO 分级微立方体由垂直排列的、高度有序的纳米片组成，进一步与 MXene/Au NPs 结合，产生协同信号放大效应，具有出色的电化学性能、大比表面积和良好的环境生物相容性。在最佳条件下，所报道的传感平台 AChE-Chit/MXene/Au NPs/MnO/MnO/GCE 可用于在较宽浓度范围内（10-10 M）检测甲胺磷，同时具有良好的线性度（R=0.995）。此外，该生物传感器具有较低的检测限（1.34×10 M），远低于欧盟设定的甲胺磷（0.01 mg/kg）最大残留限量（MRLs）。此外，还通过具有优异回收率（95.2%-101.3%）的实际样品中检测甲胺磷的可行性，证明了所提出的生物传感器的可行性。有趣的是，这些复合材料的独特结构和显著性能使它们成为用于监测农药残留或其他环境有害化学物质的各种电化学传感器的有吸引力的材料。
