Department of Nutrition and Dietetics, KTO Karatay University, Konya, Turkey. Email:
Department of Nutrition and Dietetics, University of Health Sciences, Istanbul, Turkey.
Asia Pac J Clin Nutr. 2024 Dec;33(4):481-489. doi: 10.6133/apjcn.202412_33(4).0002.
This study aimed to evaluate the effects of milk and banana given as a bedtime snack to patients with primary insomnia on sleep parameters and some biochemical parameters such as brain-derived neurotrophic factor, leptin, and ghrelin.
21 patients with insomnia who met the inclusion criteria participated in this study. The patients were divided into 3 parallel groups: banana, milk and control. The intervention group were given either 1 portion of banana or just 200 mL of whole-fat milk at bedtime. The control group did not consume any non-routine food. Venous blood samples were taken at baseline and after the study from patients to measure brain-derived neurotrophic factor, leptin and ghrelin concentrations. Sleep quality and architecture were determined by polysomnography and Pittsburg Sleep Quality Index.
Pittsburg Sleep Quality Index scores of the banana and milk group were found to be lower after intervention (p<0.05). In terms of polysomnography, the total sleep time of the milk group was found to be significantly higher than baseline. Serum ghrelin concentration of the milk group decreased significantly compared to baseline.
Bedtime milk or banana intake was effective in dealing with insomnia. Foods rich in tryptophan, such as banana and milk, given at bedtime, may improve sleep parameters and appetite hormones.
本研究旨在评估将牛奶和香蕉作为睡前零食给予原发性失眠患者对睡眠参数以及一些生化参数(如脑源性神经营养因子、瘦素和胃饥饿素)的影响。
21 名符合纳入标准的失眠患者参加了这项研究。这些患者被分为 3 个平行组:香蕉组、牛奶组和对照组。干预组在睡前分别给予 1 份香蕉或 200 毫升全脂牛奶。对照组不食用任何常规以外的食物。从患者身上采集静脉血样,以测量脑源性神经营养因子、瘦素和胃饥饿素的浓度。通过多导睡眠图和匹兹堡睡眠质量指数来确定睡眠质量和结构。
干预后,香蕉和牛奶组的匹兹堡睡眠质量指数评分较低(p<0.05)。在多导睡眠图方面,牛奶组的总睡眠时间明显高于基线。与基线相比,牛奶组的血清胃饥饿素浓度显著降低。
睡前摄入牛奶或香蕉对失眠有效。睡前摄入富含色氨酸的食物,如香蕉和牛奶,可能会改善睡眠参数和食欲激素。