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灰色链霉菌对1',2'-二氢鱼藤酮的生物转化

Biotransformations of 1',2'-dihydrorotenone by Streptomyces griseus.

作者信息

Sariaslani F S, Rosazza J P

出版信息

Appl Environ Microbiol. 1985 Feb;49(2):451-2. doi: 10.1128/aem.49.2.451-452.1985.

DOI:10.1128/aem.49.2.451-452.1985
PMID:3920966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC238425/
Abstract

Dihydrorotenone yields three major products when incubated with growing cultures of Streptomyces griseus. These were isolated by solvent extraction and characterized by spectral methods as 1',2'-dihydro-6abeta-hydroxyrotenone, 1',2'-dihydro-2',6abeta-dihydroxyrotenone, and 1',2'-dihydro-1',6abeta-dihydroxyrotenone.

摘要

二氢鱼藤酮与灰色链霉菌的生长培养物一起孵育时会产生三种主要产物。这些产物通过溶剂萃取分离出来,并通过光谱方法鉴定为1',2'-二氢-6abeta-羟基鱼藤酮、1',2'-二氢-2',6abeta-二羟基鱼藤酮和1',2'-二氢-1',6abeta-二羟基鱼藤酮。

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引用本文的文献

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Microbial transformations and bioconversions. Patents and literature.
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本文引用的文献

1
Microbial Transformations of Natural Antitumor Agents: Products of Rotenone and Dihydrorotenone Transformation by Cunninghamella blakesleeana.微生物对天然抗肿瘤剂的转化:贯叶连翘中鱼藤酮和二氢鱼藤酮转化的产物。
Appl Environ Microbiol. 1983 Feb;45(2):616-21. doi: 10.1128/aem.45.2.616-621.1983.
2
Oxidation of rotenone by Polyporus anceps laccase.
J Nat Prod. 1984 Jul-Aug;47(4):692-7. doi: 10.1021/np50034a021.
3
Microbial transformations of antitumor compounds. 1. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata.抗肿瘤化合物的微生物转化。1. 刺孢小克银汉霉将丙烯胺转化为9-羟基丙烯胺。
J Med Chem. 1974 Jun;17(6):599-602. doi: 10.1021/jm00252a006.