The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry "Ibn Omrane", Razi hospital, Manouba, 2010, Tunisia.
Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.
BMC Psychiatry. 2024 Aug 29;24(1):587. doi: 10.1186/s12888-024-06019-0.
Postpartum psychosis (PP) is a psychological emergency requiring rapid intervention, hospitalization and psychiatric management. However, PP has been neglected in the postpartum literature. Understanding the detrimental consequences of childhood trauma across mother's life span is crucial to prevent this serious condition. The study's objectives were to demonstrate the relationship between childhood trauma and postpartum psychotic experiences (PPEs) and to look over the mediating role of postnatal depression (PD) and anxiety (PA) in this relationship.
This cross-sectional study, which enrolled 438 postpartum females 4-6 weeks after delivery (mean age: 31.23 ± 5.24 years), was carried out from September 2022 to June 2023. The Arabic validated versions of the Postpartum Psychotic Experiences Scale, the Edinburgh Postnatal Depression Scale, the Perinatal Anxiety Screening Scale, and the Child Abuse Self Report Scale were used.
Both PD and PA partially mediated the correlation between psychological abuse and PPEs, and fully mediated the association between neglect and PPEs. Higher psychological abuse and neglect were significantly associated with higher PD (Beta = 1.11) and PA (Beta = 3.94), higher PD (Beta = 0.84) and PA (Beta = 0.26) were significantly associated with higher PPEs in both models, whereas greater child psychological abuse (Beta = 1.37) (but not neglect) was directly and strongly correlated with higher PPEs in all models.
The significant mediating effect of PA and PD on the association between childhood adversities and PPEs among postpartum females may offer additional therapeutic avenues to help attenuate various postpartum mental health issues and their potential serious risks on both mother and child.
产后精神病（PP）是一种需要快速干预、住院和精神科管理的心理急症。然而，PP 在产后文献中被忽视了。了解母亲一生中童年创伤的不良后果对于预防这种严重疾病至关重要。本研究的目的是证明童年创伤与产后精神病体验（PPEs）之间的关系，并探讨产后抑郁（PD）和焦虑（PA）在这种关系中的中介作用。
这是一项横断面研究，于 2022 年 9 月至 2023 年 6 月期间招募了 438 名产后 4-6 周的女性（平均年龄：31.23±5.24 岁）。使用了经过阿拉伯语验证的产后精神病体验量表、爱丁堡产后抑郁量表、围产期焦虑筛查量表和儿童虐待自我报告量表。
PD 和 PA 部分中介了心理虐待与 PPEs 之间的相关性，完全中介了忽视与 PPEs 之间的关系。较高的心理虐待和忽视与较高的 PD（Beta=1.11）和 PA（Beta=3.94）显著相关，较高的 PD（Beta=0.84）和 PA（Beta=0.26）在两个模型中均与较高的 PPEs 显著相关，而较大的儿童心理虐待（Beta=1.37）（但不是忽视）在所有模型中均与较高的 PPEs 直接且强烈相关。
PA 和 PD 在童年逆境与产后女性 PPEs 之间的关系中的显著中介作用可能为治疗产后心理健康问题及其对母婴潜在严重风险提供了额外的治疗途径。
