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类风湿关节炎患者生活质量领域与人体测量和肥胖指标之间的关联:来自伊拉克埃尔比勒单一中心的横断面研究

Association Between the Quality of Life Domains with Anthropometric and Adiposity Indices in Rheumatoid Arthritis: A Cross-Sectional Study from a Single Centre in Erbil-Iraq.

作者信息

Jalal Aryan Mohamadfatih, Mawlood Zhala Kakamin, Aref Sheelan Faroz, Al-Nimer Marwan Salih

机构信息

Department of Rheumatology, Rizgary Teaching Hospital, Kurdistan Board for Medical Specialties, Erbil, Iraq.

Department of Clinical Pharmacology, College of Medicine, University of Diyala, Baqubah, Iraq.

出版信息

Mediterr J Rheumatol. 2023 Aug 28;35(2):247-254. doi: 10.31138/mjr.230828.jaa. eCollection 2024 Jun.

Abstract

OBJECTIVE

The aim of this study was to assess the association between the anthropometric/adiposity indices or ratios with the status of quality of life (QoL) in rheumatoid arthritis (RA) patients.

METHODS

This study was carried out in the Rizgary Teaching Hospital in the Kurdistan Region of Iraq between 1 December 2021 and 31 March 2022. Seventy-five women with a mean value of 11.3 years' duration of disease were included in this study. The data relating to the demographic characteristics, disease activity score (DAS-28), biochemical measurements of the rheumatic profile, and anthropometric/adiposity indices and the ratios were included. The QoL of each patient was assessed using the WHOQOL-BREF.

RESULTS

The mean ± SD of the age and duration of disease were 49.6± 12.0, and 11.3±8.4 year. 70 out of 75 (93.3%) patients have a DAS-28 score of >2.6. The median values of the transform scores of the WHOQOL-BREF domains were less than 50. There were significant inverse correlations between BMI, and waist-to-height ratio with physical activity (r = -0.167, p = 0.05, and r = -0.168, p = 0.05, respectively). Social domain was significantly and inversely correlated with waist-to-hip, estimated total body fat, and waist-adjusted weight index. A higher BMI and a lower hip index were associated significantly with a lower mean scores of physical health

CONCLUSION

In RA patients, obesity is frequently observed. Over-weight and obese patients had a significantly lower mean score of physical health.

摘要

目的

本研究旨在评估类风湿关节炎(RA)患者的人体测量学/肥胖指数或比率与生活质量(QoL)状况之间的关联。

方法

本研究于2021年12月1日至2022年3月31日在伊拉克库尔德地区的里兹加里教学医院进行。本研究纳入了75名平均病程为11.3年的女性。纳入了与人口统计学特征、疾病活动评分(DAS-28)、风湿性疾病生化指标测量以及人体测量学/肥胖指数和比率相关的数据。使用世界卫生组织生活质量简表(WHOQOL-BREF)评估每位患者的生活质量。

结果

年龄和病程的平均值±标准差分别为49.6±12.0岁和11.3±8.4年。75名患者中有70名(93.3%)的DAS-28评分>2.6。WHOQOL-BREF各领域转换分数的中位数小于50。体重指数(BMI)和腰高比与身体活动之间存在显著负相关(r分别为-0.167,p = 0.05;r为-0.168,p = 0.05)。社会领域与腰臀比、估计的全身脂肪和腰调整体重指数显著负相关。较高的BMI和较低的臀围指数与较低的身体健康平均得分显著相关。

结论

在RA患者中,肥胖现象较为常见。超重和肥胖患者的身体健康平均得分显著较低。

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