Prada Bollineni S, Ghewade Babaji, Jadhav Ulhas, Wagh Pankaj, Alone Vivek D
Respiratory Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 Jul 29;16(7):e65705. doi: 10.7759/cureus.65705. eCollection 2024 Jul.
Infected emphysematous bullae of the lung present a diagnostic challenge due to their rarity and diverse clinical manifestations. We report the case of a 52-year-old female with chronic respiratory symptoms, including breathlessness and dry cough, persisting for six months. Imaging studies revealed characteristic features of infected emphysematous bullae, including large thick-walled cavities with air-fluid levels and associated parenchymal compression. Biomass exposure history and microbiological analysis, which isolated methicillin-resistant coagulase-negative Staphylococcus (MRCoNS), further supported the diagnosis. The patient responded well to antimicrobial therapy with doxycycline and linezolid. This case underscores the importance of considering environmental factors and multidisciplinary collaboration in managing complex respiratory conditions. Further research is warranted to elucidate optimal management strategies for infected emphysematous bullae of the lung.
肺部感染性肺大疱因其罕见性和多样的临床表现而带来诊断挑战。我们报告一例52岁女性患者，有慢性呼吸道症状，包括气促和干咳，持续6个月。影像学检查显示了感染性肺大疱的特征性表现，包括有气液平面的大的厚壁空洞及相关的实质压迫。生物质暴露史及微生物学分析分离出耐甲氧西林凝固酶阴性葡萄球菌（MRCoNS），进一步支持了诊断。患者接受强力霉素和利奈唑胺抗菌治疗后反应良好。该病例强调了在处理复杂呼吸道疾病时考虑环境因素和多学科协作的重要性。有必要进一步研究以阐明肺部感染性肺大疱的最佳管理策略。
