Leatherwork: a possible hazard to reproduction.

A retrospective study was carried out aimed at eliciting the causes of perinatal death in Leicestershire between 1976 and 1982. Case notes were reviewed and the mothers interviewed in over 1000 cases. An analysis of maternal occupations showed that leatherworkers were at increased risk of having a perinatal death, particularly from congenital malformations and macerated stillbirths, even when compared with other manual workers in the same social class. The excess risk occurred in all towns of the county where leatherwork was undertaken. Further investigation is needed of the materials used in the leather industry in order to ensure that risks are minimised. Fecund women working in the industry should be informed of any residual risk if these findings are confirmed.