Department of Otorhinolaryngology, Koshi Hospital, Biratnagar, Nepal.
Department of Otorhinolaryngology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Kathmandu Univ Med J (KUMJ). 2023;21(84):363-366.
Background There have been various studies to draw out the association between acute otitis media (AOM) and vitamin D deficiency but the results are conflicting. Objective To explore the relationship between vitamin D deficiency and acute otitis media. Method The comparative cross-sectional study was conducted in which children aged five to fifteen years were included. Sixty children diagnosed with acute otitis media were kept in group A while 60 children diagnosed with conditions other than acute otitis media were included in Group B. Then the Vitamin D level was sent in both the groups and compared. Result Fifty-four participants in group A had an insufficient level of Vitamin D while six participants had a sufficient level of Vitamin D and none had an excess level of Vitamin D while in Group B, fiftywo participants had an insufficient level of Vitamin D while eight participants had a sufficient level of Vitamin D. The mean vitamin D of the cases was 22.12 ±7.896 ng/ml, and that of the controls was 22.58 ±7.056 ng/ml for the controls (p = 0.737). Conclusion Both the children with acute otitis media and without acute otitis media had lower levels of Vitamin D in similar proportions. Therefore, we can conclude that there is no association between Vitamin D level and acute otitis media.
已有多项研究旨在探讨急性中耳炎（AOM）与维生素 D 缺乏之间的关联，但结果存在争议。目的：探索维生素 D 缺乏与急性中耳炎之间的关系。方法：采用对比性横断面研究，纳入年龄在 5 至 15 岁的儿童。将 60 名被诊断为急性中耳炎的儿童归入 A 组，60 名被诊断为非急性中耳炎的儿童归入 B 组。然后检测两组的维生素 D 水平并进行比较。结果：A 组中 54 名参与者维生素 D 水平不足，6 名参与者维生素 D 水平充足，无维生素 D 水平过量；B 组中 52 名参与者维生素 D 水平不足，8 名参与者维生素 D 水平充足。病例组的平均维生素 D 水平为 22.12±7.896ng/ml，对照组为 22.58±7.056ng/ml（p=0.737）。结论：患有急性中耳炎和不患有急性中耳炎的儿童的维生素 D 水平均较低，且比例相似。因此，我们可以得出结论，维生素 D 水平与急性中耳炎之间不存在关联。
