Mzid Khouloud, Elleuch Aida, Jallouli Dana, Chaabouni Khansa, Turki Mouna, Ayadi Fatma Makni
Laboratoire de biochimie, Hôpital Universitaire Habib Bourguiba Sfax, Sfax, 3012, Tunisie, Laboratoire de recherche « Bases moléculaires de la pathologie humaine », LR19ES13, Faculté de Médecine de Sfax, Université de Sfax.
Ann Biol Clin (Paris). 2024 Sep 19;82(4):376-386. doi: 10.1684/abc.2024.1902.
Determine the epidemiological characteristics of urolithiasis in the South region of Tunisia and the impact of age and sex on stone composition. We conducted a retrospective study including patient records whose urinary lithiasis was analyzed within the biochemistry department of CHU Habib Bourguiba of Sfax (2011-2020). Stone analysis was performed using a stereomicroscope and infrared spectroscopy. A total of 1127 stones were analyzed. The sex ratio was 2,6. Renal Colic pain was the most common symptom (48,3%). The most frequent localization of the stones (84.6%) was the upper urinary tract. Whewellite was the most common component (64.1%). The study of stone component according to age showed a decrease in the frequency of weddellite (p = 0,024) and an increase in the frequency of uric acid stones with age (p < 0,001). Whewellite was more frequent in men (p = 0.022) and, notably in our series, uric acid was significantly more frequent in women (p < 0.001). The epidemiological profile of urolithiasis in south of Tunisia is similar to that observed in industrialized countries.
确定突尼斯南部地区尿石症的流行病学特征以及年龄和性别对结石成分的影响。我们进行了一项回顾性研究，纳入了在斯法克斯哈比卜·布尔吉巴大学医院（CHU Habib Bourguiba）生物化学科进行尿液结石分析的患者记录（2011 - 2020年）。使用体视显微镜和红外光谱进行结石分析。共分析了1127颗结石。男女比例为2.6。肾绞痛是最常见的症状（48.3%）。结石最常见的部位（84.6%）是上尿路。水草酸钙是最常见的成分（64.1%）。根据年龄对结石成分的研究显示，二水草酸钙的频率降低（p = 0.024），尿酸结石的频率随年龄增加（p < 0.001）。水草酸钙在男性中更常见（p = 0.022），值得注意的是，在我们的系列研究中，尿酸在女性中明显更常见（p < 0.001）。突尼斯南部尿石症的流行病学特征与工业化国家观察到的相似。
