类葡萄球菌素肽Pep 5对细菌细胞和细胞质膜囊泡膜电位的影响。
Influence of the staphylococcinlike peptide Pep 5 on membrane potential of bacterial cells and cytoplasmic membrane vesicles.
作者信息
Sahl H G
出版信息
J Bacteriol. 1985 May;162(2):833-6. doi: 10.1128/jb.162.2.833-836.1985.
Abstract
The staphylococcinlike peptide Pep 5 rapidly abolished the membrane potential of bacterial cells; active transport of amino acids by cytoplasmic membrane vesicles was inhibited and preaccumulated amino acids were released upon the addition of Pep 5. Artificial asolectin vesicles were not impaired by the peptide. It is concluded that the cytoplasmic membrane is the primary target of Pep 5.
摘要
类葡萄球菌素肽Pep 5能迅速消除细菌细胞的膜电位；细胞质膜囊泡对氨基酸的主动转运受到抑制，添加Pep 5后，预先积累的氨基酸会被释放出来。人工大豆卵磷脂囊泡不受该肽的影响。得出的结论是，细胞质膜是Pep 5的主要作用靶点。
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