The University of Toledo, OH, USA.
The University of Toledo Medical Center, OH, USA.
J Investig Med High Impact Case Rep. 2024 Jan-Dec;12:23247096241272030. doi: 10.1177/23247096241272030.
Bilateral retinal metastasis is a rare disease that represents less than 1% of ocular metastases. Additionally, the prevalence of ocular metastases overall is only 5% to 10%. It is uncommonly found due to the absence of a lymphatic system in the eye. Ocular metastasis is spread hematogenously and the retina only receives 5% of blood flow, contributing to the rarity of this condition. Retinal metastasis has been reported to mimic symptoms of retinitis which include watery eye discharge, conjunctival injection and pain with ocular movement which leads to a harder diagnosis. Treatment options for retinal metastasis include systemic chemotherapy, intravitreal chemotherapy, and plaque radiotherapy. However, despite treatment, retinal metastasis often has a poor prognosis. This is a case of a 65-year-old woman with a history of breast carcinoma status post mastectomy who initially presented with metastatic infiltration of the lung and liver. However, she later developed an interesting case of retinal metastasis, which presented as symptoms of retinitis and indicated widespread dissemination of an unknown primary neoplasm.
双侧视网膜转移是一种罕见疾病，占眼部转移的比例不到 1%。此外，眼部转移的总体发生率仅为 5%至 10%。由于眼睛中没有淋巴管，因此很少发生这种疾病。眼部转移是通过血液传播的，而视网膜仅接收 5%的血流量，这也是这种情况罕见的原因。视网膜转移已被报道模仿视网膜炎的症状，包括水样眼分泌物、结膜充血和眼球运动时疼痛，这导致了更难诊断。视网膜转移的治疗选择包括全身化疗、眼内化疗和放射性敷贴治疗。然而，尽管进行了治疗，视网膜转移通常预后不良。这是一例 65 岁女性，有乳腺癌病史，已行乳房切除术，最初表现为肺和肝转移浸润。然而，她后来出现了一例有趣的视网膜转移病例，表现为视网膜炎的症状，并提示广泛播散的未知原发性肿瘤。
