Li Danfeng, Luo Lifu, Yang Bo, Xiao Jun
Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Front Oncol. 2025 Aug 4;15:1616331. doi: 10.3389/fonc.2025.1616331. eCollection 2025.
Retinal metastasis is an exceedingly rare manifestation of systemic cancer, accounting for less than 1% of ocular metastases. Lung adenocarcinoma is among the primary tumors that can metastasize to the retina, though such cases are seldom reported. We present a 70-year-old male with a history of lung adenocarcinoma who presented with a decline in vision in his left eye. Fundus examination revealed a large yellow-white lesion with hemorrhage in the macula and temporal retina. Multimodal imaging, including optical coherence tomography (OCT) and fluorescein angiography (FA), confirmed the diagnosis of retinal metastasis. This case underscores the importance of considering retinal metastasis in cancer patients with visual disturbances. Early diagnosis through comprehensive ophthalmic evaluation is crucial to avoid misdiagnosis.
视网膜转移是全身癌症极为罕见的一种表现形式，占眼部转移的比例不到1%。肺腺癌是可转移至视网膜的原发性肿瘤之一，不过此类病例鲜有报道。我们报告了一名70岁男性，有肺腺癌病史，因左眼视力下降前来就诊。眼底检查发现黄斑和颞侧视网膜有一个伴有出血的大的黄白色病变。包括光学相干断层扫描（OCT）和荧光素血管造影（FA）在内的多模态成像确诊为视网膜转移。该病例强调了在有视觉障碍的癌症患者中考虑视网膜转移的重要性。通过全面的眼科评估进行早期诊断对于避免误诊至关重要。
